نتایج جستجو برای: lung function impairment
تعداد نتایج: 1579717 فیلتر نتایج به سال:
BACKGROUND A study was undertaken to establish the chronic effect of initial and recurrent treated pulmonary tuberculosis on impairment of lung function. METHODS A total of 27 660 black South African gold miners who had reliable pulmonary function tests from January 1995 to August 1996 were retrospectively followed for the incidence of pulmonary tuberculosis to 1970. The lung function measure...
Recent evidence suggests that chemokine CXCL12, the cognate agonist of chemokine receptors CXCR4 and ACKR3, reduces thrombin-mediated impairment of endothelial barrier function. A detailed characterization of the effects of CXCL12 on thrombin-mediated human lung endothelial hyperpermeability is lacking and structure-function correlations are not available. Furthermore, effects of other CXCR4/AC...
Abstract Background The effects of visceral adiposity on decreased lung function have drawn much attention. Recently, the index (VAI) has been proposed as a fat distribution and dysfunction marker. However, relationship between VAI not investigated. objective study was to analyze association evaluate potential predictor function. Methods We collected data from population-based 1786 subjects age...
BACKGROUND There is a paucity of studies comparing asthma and chronic obstructive pulmonary disease (COPD) based on thoracic quantitative computed tomographic (QCT) parameters. OBJECTIVES We sought to compare QCT parameters of airway remodeling, air trapping, and emphysema between asthmatic patients and patients with COPD and explore their relationship with airflow limitation. METHODS Asthm...
Sarcoidosis is a granulomatous disease involving multiple organs with unknown cause. More than 90% of patients with sarcoidosis have lung disease [1–3]. However, respiratory function in patients with sarcoidosis often remains normal, even when pulmonary parenchymal involvement is extensive. Not only the lung parenchyma but also the lung airways are involved, which sometimes makes it difficult t...
The aim of the present study was to analyse determinants of lung function in 7-yr-old children with different wheezing patterns (early, persistent and late onset) in a prospective cohort study. The German Multicentre Allergy Study (MAS) followed 1,314 children from birth onwards. Annual assessments included clinical check-ups, a structured interview and repeated measurement of specific immunogl...
BACKGROUND Obesity and asthma are associated. There is a relationship between lung function impairment and the metabolic syndrome. Whether this relationship also exists in the morbidly obese patients is still unknown. Hypothesis. Low-grade systemic inflammation associated with the metabolic syndrome causes inflammation in the lungs and, hence, lung function impairment. METHODS This is cross-s...
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