Tumor-targeted therapies are playing growing roles in cancer research. The exploitation of these powerful therapeutic modalities largely depends on the discovery of tumor-targeting ligands. Phage display has proven a promising high throughput screening tool for the identification of novel specific peptides with high binding affinity to cancer cells. In the present study, we describe the use of ...

Lung cancer continues to be the leading case of cancer deaths in the United States. In patients with resectable non-small cell lung cancer, surgical resection is the treatment of choice. An accurate preoperative general and pulmonary-specific evaluation is essential as postoperative complications and morbidity of lung resection surgery are significant. After confirming anatomic resectability, p...

The surgical treatment of the lung was developed primarily for pulmonary tuberculosis until the 1960s but was used for primary lung cancer in the 1970s. The incidence of lung cancer will increase in the next 30 years worldwide, and the annual incidence of lung cancer in Japan is expected to increase to about 150,000 by 2015. Over the past 50 years, pulmonologists have performed clinicopathologi...

OBJECT Metastatic epidural spinal cord compression (MESCC) is a relatively common and debilitating complication of metastatic disease that often results in neurological deficits. Recent studies have supported decompressive surgery over radiation therapy for patients who present with MESCC. These studies, however, have grouped all patients with different histological types of metastatic disease ...

SUMMARY OBJECTIVE: The aim of this retrospective study was to investigate the correlation transiently elevated postoperative serum cancer antigen 125 levels and prognosis in patients with non-small cell lung cancer. METHODS: A total 181 normal preoperative were statistically summarized study. RESULTS: Out analyzed patients, 22 (12.2%) showed elevation within one month after surgery. Serum level...

Abstract Background Cigarette smoking is a well-known habitual risk factor for lung cancer. Lung cancer resections make up the majority of BRI Thoracic Surgery admissions. Smoking has negative impact on long term survival and disease progression patients increasing recurrence secondary tumours following surgery with curative intent. Method Retrospective analysis all discharged from thoracic dur...

Lung cancer is one of the most lethal forms of cancer worldwide. Even in this era of advances in cancer treatment modalities, the mortality of lung cancer continues to rise. Lung cancer is notorious for detection usually in an advanced stage where surgery has very little role. Targeted therapy in the form of various classes of tyrosine kinase inhibitors offer a great option for better lung canc...

Introduction: lung cancer is the deadliest and the costliest cancer in the world. In this study, we have tried to compare the situation of this disease in several countries by considering the most important risk factor of lung cancer (smoking cigarette). Method: This is a comparative study, a comprehensive one which was done on lung cancer rates in four countries, Iran, Turkey, England and UAS...

OBJECTIVES To improve surgical outcomes, clinicians must provide optimal perioperative care for comorbidities identified as significant factors in risk models for patients undergoing lung cancer surgery. METHODS We reviewed trends in perioperative care for idiopathic pulmonary fibrosis, cardiovascular diseases, and end-stage renal diseases in patients undergoing lung cancer surgery, as large ...

introduction: radiation therapy following breast conserving surgery is one of the most common procedures performed in any radiation oncology department. a tangential parallel-opposed pair is almost always the technique of choice for this purpose. this technique is often performed based on 3d treatment planning. the aim of this study was to compare 3d treatment planning for two different energie...