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The Wnt family of secreted glycoproteins plays a critical role in developmental processes including axis patterning, cellular proliferation, planar cell polarity, cell migration, cell fate specification, and neuronal development. In adults, Wnt signaling is involved in tissue homeostasis, regeneration, and stem/progenitor cell function. Moreover, elevated or attenuated Wnt signaling is found in...
Large conductance Ca-activated K (BK) channels are activated by membrane depolarization and intracellular Ca and Mg (Latorre and Brauchi, 2006; Lu et al., 2006; Salkoff et al., 2006; Cui et al., 2009; for review see Magleby, 2003). Once activated, the K efflux through the opened channel drives the membrane potential in the negative direction. Through this mechanism, BK channels sense both depol...
Cutaneous leishmaniasis caused by Leishmania venezuelensis (Bonfante-Garrido, 1980) is endemic in dry urban areas in the central part of western Venezuela (R Bonfante-Garrido et al. 1992 Trans R Soc Trop Med Hyg 86: 141-148). This disease has been also found in cats (R BonfanteGarrido et al. 1996 Rev Cient Fac Cienc Veter Univ Zulia Venezuela 3: 187-190). Lutzomyia olmeca bicolor (Fairchild & T...
In recent years, increasing attention has been focused on the study of dynamical systems, often with time delay, which model in population dynamics [Chen & Blackmore, 2002; Gopalsamy, 1992; Yang, 1993; Matin & Ruan, 2001; May, 1973], physics and mechanics [Cahlon et al., 1997], remote control [Ryabov, 1960], radiation damping [Chicone et al., 2001], and so on and so forth. Such systems attract ...
Topicality of the ionizing radiation impact on organisms is conditioned by Nuclear Power Plants (NPP), releasing of various technogenic radionuclides into the environment during the operational period in different in different way. Chronic exposure of low doses of ionizing radiation to biota is an invisible, however, inevitable factor of the environment (Lu et al., 2006; Geras’kin et al., 2007;...
Recently, a new Leishmania amazonensis focus was described in a sub-Andean region (1,450-2,100 meters above sea level) of Bolivia. In this area, three anthropophilic sandfly species were identified: Lutzomyia nuneztovari anglesi Le Pont & Desjeux, 1984, which represented 86-99% of the captures, Lu. galatiae Le Pont et al., 1998, and Lu. shannoni Dyar 1929. Only Lu. nuneztovari anglesi was found...
BACKGROUND Elevated plasma and urine endothelin-1 (ET-1) levels have been reported in renal failure and may be involved in renal disease progression. We investigated whether these changes are related to increased vascular and renal ET-1 production in the pole resection remnant kidney model of chronic renal failure in the rat. METHODS Uraemic Wistar rats were prepared by surgical renal mass 5/...
The electron hosing instability in the blow-out regime of plasma-wakefield acceleration is investigated using a linear perturbation theory about the electron blow-out trajectory in Lu et al. [in Phys. Rev. Lett. 96, 165002 (2006)10.1103/PhysRevLett.96.165002]. The growth of the instability is found to be affected by the beam parameters unlike in the standard theory Whittum et al. [Phys. Rev. Le...
سل یک بیماری عفونی است که بوسیله باسیل مایکوباکتریوم توبرکولوزیس1 ایجا د می گردد . از نظرآماری می توان گفت که باسیل توبرکلوزیس در هر ثانیه یک نفر را آلوده می کند. برآورد و تخمین سازمان بهداشت جهانی (who) نشان می دهد که سالیانه حدود سه میلیون نفر بر اثر بیماری سل فوت می کنند . کشور ایران با تعداد 5/17 مورد در هر یک صد هزار نفر مقام هفدهم را در سال 1998 میلادی احراز کرده است (بنی فضل و همکاران،1...
INTRODUCTION The tracheal and bronchiolar airways of mammals are essential for providing defense against inhaled pathogens and external environmental insults, such as cigarette smoke and pollution. The pseudostratified epithelium lining the trachea and proximal bronchiolar airways is composed of multiple cell lineages, including secretory and ciliated epithelium as well as basal cells, which ac...
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