Sir: As the present methods for determination of concentrations of penicillins, and activities of penicillin-metabolising enzymes, are not completely satisfactory we examined the possibility of using the LOWRY reaction with penicillins1) for this purpose. All penicillins tested reacted with LOWRY reagent. Table 1 shows that ampicillin, 6-aminopenicillanic acid (6-APA), carbenicillin and several...

Seven current methods of protein quantitation, Bradford (standard, micro, and 590/450 nm ratio), Lowry, bicinchoninic acid (BCA), UV spectrophotometry at 280 nm, and Quant-iT fluorescence-based determination, were compared with regard to their susceptibility to interferences due to the presence of suspended and not easily detectable clay particles. Bovine serum albumin (BSA) and Na-Wyoming mont...

The Coffin-Lowry syndrome is a rare cause of mental retardation recognised by its distinctive facial and digital features. We have observed an unusual, non-epileptic, cataplexy-like phenomenon in three subjects with the syndrome and we speculate that this feature may go unrecognised. We also provide evidence of neuromuscular dysfunction as part of the phenotype by showing abnormalities on muscl...

This paper presents a parallelized genetic algorithm for the calibration of Lowry model based on a maximum likelihood approach. A case study for the city of Hong Kong was employed for demonstrating the performance of the parallelized genetic algorithm, in terms of two commonly used performance measures: speedup and eciency. The genetic algorithm is particularly suitable for implementation unde...