Male Macaca nemestrina were studied In an experiment with a 2 X 2 factorial design. Diets contained low vs high cholesterol levels (0.3 vs 1.0 mg/Kcal) and no ethanol or ethanol, as 36% of the calories substituted isocalorically for carbohydrate. After receiving their diets for 18 months, the monkeys had blood samples drawn for lipoproteln analyses, and then were killed for evaluation of the ex...

Male Macaca nemestrina were studied in an experiment with a 2 x 2 factorial design. Diets contained low vs high cholesterol levels (0.3 vs 1.0 mg/Kcal) and no ethanol or ethanol, as 36% of the calories substituted isocalorically for carbohydrate. After receiving their diets for 18 months, the monkeys had blood samples drawn for lipoprotein analyses, and then were killed for evaluation of the ex...

background: vascular calcification is an important stage in atherosclerosis. during this stage, vascular smooth muscle cells (vsmc) synthesize many osteogenic factors such as osteonectin (encoded by sparc). oxidative stress plays a critical role in atherosclerosis progression, and its accumulation in the vascular wall stimulates the development of atherosclerosis and vascular calcification. the...

background: oxidative modification of low-density lipoprotein (ldl) appears to be an early step in the pathogenesis of atherosclerosis. meanwhile, myeloperoxidase (mpo)-catalyzed reaction is one of the potent pathway for ldl oxidation in vivo. the aim of this study was to evaluate in vitro antioxidant effects of vitamins c and e on ldl oxidation mediated by mpo. methods: mpo was isolated from f...

this article reports a study of the thermo-oxidation and biodegradation in the soil of low-density polyethylene/starch films (ldpe/starch) by infrared spectroscopy: films of ldpe/starch blends of different composition (starch content range from 0 to 15% w/w),were prepared and exposed to thermo-oxidation at different temperatures at 80, 90 and 100°c,and buried in the soil of public dump during 3...

Hepatitis C virus (HCV) particles found in vivo are heterogeneous in density and size, but their detailed characterization has been restricted by the low titre of HCV in human serum. Previously, our group has found that HCV circulates in blood in association with very-low-density lipoprotein (VLDL). Our aim in this study was to characterize HCV RNA-containing membranes and particles in human li...

By equilibrium density gradient ultracentrifugation, we analyzed the chemical composition and particle size of low density lipoproteins (LDLs) in 16 subfractions separated from the LDL fractions (1.019 less than d less than 1.063 g/ml) of two hyperalphalipoproteinemic patients who had a deficiency of cholesteryl ester transfer protein (CETP). The LDLs of these patients comprised a group of hete...

We identified the first insertion mutation that specifies an apolipoprotein (apo)B truncation, apoB-70.5, in a father and son with hypobetalipoproteinemia (total and low-density lipoprotein [LDL] cholesterol < 5th percentile, plasma apoB levels approximately one third of normal). The mutation is due to insertion of an adenine (A) into a 7-A repeat between cDNA position 9754 and 9760 of the apoB...