BACKGROUND Anorectal dysfunction may occur following sphincter-saving resection for rectal carcinoma. The dysfunction may present clinically with increased stool frequency and varying degrees of fecal incontinence. It is postulated that these presentations come about from reduced neorectal capacity, as well as internal anal sphincter injury, during transanal instrumentation or through damage to...

This is a multi-center retrospective study of patients underwent low anterior resection for rectal cancer. Ileostomy had been done to protect lying Colo-rectal anastomosis, closure ileostomy delayed in some due patient own will, surgical complications (anastomotic leak) or coarse chemotherapy. aimed find the effect temporary on post-operative bowel defunction which called Low syndrome (LARS), a...

OBJECTIVE To identify the risk factors associated with anastomotic leakage following an anterior resection for rectal cancer. METHODS Between June, 1999 and June, 2009, 628 patients underwent anterior resection for rectal cancer. A retrospective study of the cases was performed to identify the risk factors for anastomotic leakage following the resection. RESULTS The overall incidence rate o...

INTRODUCTION In colorectal surgery, the most feared complication is anastomotic leakage (AL), which is associated with a high morbidity and mortality. In this study, we focus on treatment of perianastomotic abscess following AL after low anterior resection (LAR) of rectal cancer. In the literature, conservative irrigation regimes are reported to perdure for months and some even years and to be ...

UNLABELLED Anastomotic leak after anterior rectal resection for cancer is one of the most dangerous complications of the procedure. Protective stomy is a way to avoid life-threatening consequences of this complication. The procedure is still under evaluation.The aim of the study was to evaluate the usefulness of forming a protective stomy as part of anterior rectal cancer resection on the basis...

The follicle cell monolayer that encircles each developing Drosophila oocyte contributes actively to egg development and patterning, and also represents a model stem cell-derived epithelium. We have identified mutations in the receptor-like transmembrane tyrosine phosphatase Lar that disorganize follicle formation, block egg chamber elongation and disrupt Oskar localization, which is an indicat...

International collaboration is important in healthcare quality evaluation; however, few international comparisons of general surgery outcomes have been accomplished. Furthermore, predictive model application for risk stratification has not been internationally evaluated. The National Clinical Database (NCD) in Japan was developed in collaboration with the American College of Surgeons National S...