The nuclear Overhauser effect (NOE) is a powerful tool in molecular structure elucidation, combining the subtle chemical shift of NMR and three-dimensional information independent connectivity. Its usage for intermolecular studies, however, fundamentally limited by an unspecific long-ranged interaction behavior. This joint experimental computational work shows that proper selection interacting ...

purpose: to compare the short and long-term efficacy and complications of releasable suture vs conventional interrupted suture for scleral flap in trabeculectomy. methods: in a prospective randomized clinical trial, 42 eyes of 42 consecutive patients requiring trabeculectomy for uncontrolled primary glaucoma underwent conventional trabeculectomy (group a) and trabeculectomy with releasable sutu...

Listeners must cope with a great deal of variability in the speech signal, and thus theories of speech perception must also account for variability, which comes from a number of sources, including variation between accents. It is well known that there is a processing cost when listening to speech in an accent other than one's own, but recent work has suggested that this cost is reduced when lis...

patients  with  primary  antibody  deficiencies  (pad)  are  susceptible  to  recurrent  and chronic infections and a variety of complications. this study was performed to assess quality of life (qol) of pad patients who were under long term treatment and regular follow-up.thirty six adults with proved diagnosis of pad, who had received regular intravenous immunoglobulin replacement therapy, we...

PURPOSE Combination therapy with an α-1-adrenergic blocker and phosphodiesterase type 5 inhibitors (PDE5Is) has shown improvements in lower urinary tract symptoms (LUTS) with negligible side effects. Nonetheless, decisive advantages in symptom improvement were insufficient, and there were no clinical differences between long- or short-acting PDE5Is in combination with combination medication. ...

objective(s): there is controversial evidence about the effect of methamphetamine (meth) on spatial memory. we tested the time- dependent effects of meth on spatial short-term (working) and long-term (reference) memory in meth –sensitized and withdrawn rats in the morris water maze. materials and methods: rats were sensitized to meth (2 mg/kg, daily/5 days, sc). rats were trained in water maze ...

Introduction Landau-Kleffner syndrome, aka acquired epileptic aphasia in children, is a type of epilepsy in which the most characteristic symptom is word deafness (aphasia) evolving into auditory agnosia and/or mutism. Since Landau-Kleffner syndrome was discovered by Dr. Landau and Dr. Kleffner in 1957 [1], there have been some case studies examining language outcomes in children suffering from...