Heart disease represents one of the main challenges in modern medicine with insufficient treatment options. Whole genome sequencing allowed for discovery several classes non-coding RNA (ncRNA) and widened our understanding regulatory circuits. The intrinsic ability long ncRNAs (lncRNAs) circular RNAs (circRNAs) to regulate gene expression by a plethora mechanisms make them candidates conceptual...

There are many evidences that human serum paraoxonase activity modifies plasma lipid profile and paraoxonase has an antiatherogenic property. Non-selective beta-blockers affect plasma lipid profile too, but they have atherogenic property when patients take these drugs in long term. In this study the effect of propranolol, a non-selective beta-blocker, on paraoxonase activity was investigated. L...