Advanced cervical carcinoma (CC) is one of the most commonly diagnosed cancers in women, especially in developing countries, and it is still remains a major problem in oncology due to treatment failure and distant metastasis. Cervical cancer occurs with high morbidity and mortality in Uyghur women in the Xinjiang region, which is considered a high incidence disease in Xinjiang (Ma et al., 2001;...

Cervical cancer continues to be a significant health burden worldwide. Globally, the majority of cancers are locally advanced at diagnosis; hence, radiation remains the most frequently used therapeutical modality. Currently, the value of adding cisplatin or cisplatin-based chemotherapy to radiation for treatment of locally advanced cervical cancer is strongly supported by randomized studies and...

Choo YC (Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, U.S.A.). Chemotherapy in advanced primary and recurrent cervical carcinoma. Int J Gynaecol Obstet 20: 417.-423, 1982 Chemotherapy in carcinoma of the cervix continues to be a therapeutic challenge. The diversified treatment programs from one institution and t...

BCC: basal cell carcinoma HPI: hedgehog pathway inhibitors laBCC: locally advanced basal cell carcinoma RT: radiotherapy INTRODUCTION Hedgehog pathway inhibitors (HPIs) are indicated for locally advanced basal cell carcinoma (laBCC) and metastatic basal cell carcinoma with reported treatment length of 5.5months tomore than 5 years. The definition of laBCC is historically ill described and only ...

Sir: Cervical cancer is the second most common malignancy in women worldwide. In developing countries, most cases are still diagnosed with locally advanced disease, so the great challenge in the management of advanced cervical cancer remains the control and prevention of distant metastasis. A prominent feature of clinically advanced cervical cancers is hypoxia which is, therefore, a therapeutic...