The present study deals with the synthesis andfunctionalization of mesoporous silica nanoparticles as drug delivery platforms. SBA-15 nanorods with high surface area (1010 m2g-1) were functionalized by post grafting method using 3-mercaptopropyl trimethoxysilane (MPTS). The parent and thiol-functionalized SBA-15 nanorods were used as nanocarriers for an anticancer drug (gemcitabine). The charac...

A model of the human foot is proposed in which the foot is represented as eight rigid segments and eight monocentric, single-degree-of-freedom joints. The soft tissue under the foot is divided into seven independent sites of contact, or loading, and each of these is modelled as a nonlinear spring and a nonlinear damper in-parallel. The model was used to estimate the kinematics and kinetics of t...

Infrared temperature-sensing techniques have the major advantages of virtually no interference of the sensor with the sensed phenomenon and fast inherent response. On the other hand, infrared temperature sensing, as a superficial measurement technique, does not indicate the specimen’s core temperatures, and hence a complementary thermal analysis is required. A thermal analysis of surface temper...

For detection of low concentrations of analytes in complex biological matrices using optical biosensors, a high surface loading with capture molecules and a low nonspecific binding of nonrelevant matrix molecules are essential. To tailor biosensor surfaces in such a manner, poly(ethylene glycols) (PEG) in varying lengths were immobilised covalently onto glass-type surfaces in different mixing r...

In this paper, a two-dimensional computational model is proposed for predicting the initiation position and propagation path of subsurface crack of spur gear tooth flank. In order to simulate the contact of teeth, an equivalent model of two contacting cylinders is used. The problem is assumed to be under linear elastic fracture mechanic conditions and finite element method is used for numerical...

As a limiting nutrient in aquatic systems, phosphorus (P) plays an important role in controlling freshwater and coastal primary productivity and ecosystem dynamics, increasing frequency and severity of harmful and nuisance algae blooms and hypoxia, as well as contributing to loss of biodiversity. Although dissolved inorganic P (DIP) often constitutes a relatively small fraction of the total P p...