the oxidative modification of low density lipoprotein (ldl) may play an important role in atherogenesis. antioxidants that can prevent ldl oxidation may act as antiatherogens. our understanding of the mechanism of ldl oxidation and factors that determine its susceptibility to oxidation is still incomplete. copper is a candidate for oxidizing ldl in atherosclerotic lesions. the binding of copper...

background: studies demonstrated controversial results on subclinical hypothyroidism (sch) regarding lipid profile alteration with or without levothyroxine treatment. the purpose of this study is to investigate the effects of levothyroxine on serum lipids in sch. materials and methods: one hundred patients with sch referred to taleghani hospital in kermanshah were recruited and randomly assigne...

abstract background and objective: t3 resin uptake test indicates the availability of thyroxin binding globulin (tbg), which is the carrier of a large amount of t3 and t4 in blood. we aimed to study the relationship between serum t3 resin uptake and serum lipids profile. material and methods: the participants aged 14.80 ± 38.29 were both males (59 29.5%) and females (141 70.5 %). t3 resin uptak...

background: it is well established that oxidative modification of low density lipoprotein (ldl) plays a causal role in human atherogenesis and the risk of atherosclerosis is increased in patients with diabetes mellitus. we examined the in vitro effect of glucose on native and glycated ldl oxidation using copper ion dependent oxidation system. methods: in this study, ldl was isolated from plasma...

OBJECTIVE Identification of lipoprotein subfractions in lipoprotein profile by Lipoprint LDL system, where a lipoprotein(a), an independent risk factor for the development of cardiovascular disease, migrates with. The concentration of lipoprotein(a) in serum over 0.3 g/l increases the risk of athero-thrombosis and a brain stroke. The persons with increased levels of lipoprotein(a) and contempor...

Male Macaca nemestrina were studied in an experiment with a 2 x 2 factorial design. Diets contained low vs high cholesterol levels (0.3 vs 1.0 mg/Kcal) and no ethanol or ethanol, as 36% of the calories substituted isocalorically for carbohydrate. After receiving their diets for 18 months, the monkeys had blood samples drawn for lipoprotein analyses, and then were killed for evaluation of the ex...