Background: The prevalence of vitiligo has been reported to range from 0.1% 8% worldwide, and linked some autoimmune non-autoimmune diseases. This study aimed estimate the associated comorbidities in adults Shanghai.

Age patterns of incidence of major age-associated diseases (cancer, diabetes, cardioand cerebrovascular, and neurodegenerative diseases) are calculated in the U.S. elderly population (aged 66-107) using ICD-9 diagnosis reported in Medicare records linked to 1982 to 1999 NLTCS survey respondents. Detailed sensitivity analysis, including effects of latent censoring, incorrect age reporting, and o...

inflammation plays a major role in coronary artery disease (cad). currently, it is unclear, whether cytomegalovirus (cmv) infection is associated with the risk of the atherosclerosis. the aim of this study was to determine the prevalence of anti- cmv antibodies in cad and non cad patients undergoing artery bypass surgery. sera from 157 patients who underwent coronary angiography were tested for...

Phosphoinositides are implicated in the regulation of a wide variety of cellular functions. Their importance in cellular and organismal physiology is underscored by the growing number of human diseases linked to perturbation of kinases and phosphatases that catalyze interconversion from one phosphoinositide to another. Many such enzymes are attractive targets for therapeutic interventions. Here...

GENETIC DISORDERS ARE TRADITIONALLY CATEGORIZED INTO THREE MAIN GROUPS: single-gene, chromosomal, and multifactorial disorders. Single gene or Mendelian disorders result from errors in DNA sequence of a gene and include autosomal dominant (AD), autosomal recessive (AR), X-linked recessive (XR), X-linked dominant and Y-linked (holandric) disorders. Chromosomal disorders are due to chromosomal ab...

Vitamin D is a sunshine vitamin and is key player in Bone diseases (like Osteoporosis,Osteoarthritis,Rheumatoid Arthritis),Autoimmune diseases,Chronic diseases like Diabetes Mellitus,Hypertension,CardiovascularDiseases,Metabolic Syndromes and Cystic fibrosis Calcium,Magnesium and Phosphorus are the key ions whose interplay is closely linked to each other in positive bone metabolism and Vitamin ...

X-Linked adrenoleukodystrophy is the most common peroxisomal disorder with different phenotypes among patients carrying the same ABCD1 mutation. There were previously reported associations of X-linked adrenoleukodystrophy with autoimmune disorders. The authors describe Guillain Barré syndrome in a child with X-linked adrenoleukodystrophy. The available evidence does not permit conclusion concer...

Previously the concept of genetics was applied to a limited number of diseases with obvious phenotypes where simple people use to observe and relate. It was never easy to establish a clear cut of heritability range between genetic variation and a risk of suffering from a complex disorder due to many reasons including but not limited to; gene variations, non-linear interactions between genetic v...

As the world struggles to cope with communicable diseases like TB and HIV/AIDS, noncommunicable diseases (including mental disorders and injuries) are rapidly on the rise. The rapid rise in noncommunicable diseases represents one of the major health challenges to global economic and social development. It disproportionately affects those in greatest need – the poor, often women and children, an...