PURPOSE A key factor limiting the effectiveness of radiation therapy is normal tissue toxicity, and recent preclinical data have shown that ultra-high dose rate irradiation (>50 Gy/s, "FLASH") potentially mitigates this effect. However, research in this field has been strongly limited by the availability of FLASH irradiators suitable for small animal experiments. We present a simple methodologi...

There is a great deal of interest in image-guided radiotherapy (IGRT), and to advance the state of IGRT, an integrated linear accelerator-magnetic resonance (linac-MR) system has been proposed. Knowledge of the radiofrequency (RF) emissions near a linac is important for the design of appropriate RF shielding to facilitate the successful integration of these two devices. The frequency spectra of...

BACKGROUND Both fractionated external beam radiotherapy and single fraction radiosurgery for pituitary adenomas are associated with the risk of hypothalamic-pituitary (HP) axis dysfunction. OBJECTIVE To analyze the effect of treatment modality (Linac, TomoTherapy, or gamma knife) on hypothalamic dose and correlate these with HP-axis deficits after radiotherapy. METHODS Radiation plans of pa...

Design and experimental results are presented from two high power microwave generation experiments utilizing a high repetition rate induction linac generated electron beam. A relativistic klystron has generated more than 100 MW microwave pulses in X-band for 50 ns without pulse shortening or breakdown. Design studies for the first cyclotron autoresonance maser (CARM) amplifier using an inductio...

Objective: Modelling linear accelerator (linac) photon beams using the Monte Carlo (MC) technique is presently most precise with which to calculate radiotherapy beam data. Complicated treatment plans can be achieved by Agility multileaf collimator. The focus of this study model a linac, integrated an head, EGSnrc MC code and investigate its accuracy compared actual measurements. Methodology: A ...

A conceptual design for a multistaged 1-GeV IFEL laser-driven accelerator (laser linac) was developed using the Staged Electron Laser Acceleration (STELLA) inverse free electron laser (IFEL) model created at STI Optronics. A comparison with the UCLA TREDI model yields good agreement with the STELLA model. The 1-GeV IFEL laser linac consists of an IFEL buncher for forming microbunches and four I...

Trigeminal neuralgia (TN) is a disabling pain condition that has classically been treated using either surgical or medical techniques. Several researchers have shown that stereotactically delivered radiation can be an effective tool in the amelioration of this condition. For these studies, the Gamma Knife was used to deliver the radiation treatment. The target location was designated as the pro...

It is necessary to consider the effect of photoneutrons produced by photonuclear reactions in shielding calculation a medical linac room with incident electron greater than 10 MeV. For copper and tungsten used as target materials linac, we compared experimental data evaluated four reaction files photoneutron production cross sections. We also calculated results using on angular distributions em...

Stereotactic body radiation therapy (SBRT) employs precision target tracking and image-guidance techniques to deliver ablative doses of radiation to localized malignancies; however, treatment with conventional photon beams requires lengthy treatment and immobilization times. The use of flattening filter-free (FFF) beams operating at higher dose rates can shorten beam-on time, and we hypothesize...

These days the linac at the Stanford Linear Accelerator Center (SLAC) is mainly an injector for the PEP-II rings. But besides the electrons and positrons for PEP-II, it provides a 30 GeV electron or positron beam to the end of the linac into the FFTB (Final Focus Test Beam) area or creates a test beam for the A-Line. In the FFTB tunnel there are two plasma experiments installed, which have demo...