Background: Neuronal topographic map formation requires appropriate selection of axonal trajectories at intermediate choice points prior to target innervation. Axons of neurons in the spinal cord lateral motor column (LMC), as defined by a transcription factor code, are thought to innervate limb target tissues exclusively. Axons of the medial and lateral LMC divisions appear to execute a binary...

objective(s): the aim of study was to determine history of genitourinary diseases in war related bilateral lower limb amputees who were injured during iran-iraq war (1980-1988).   methods: subjects with war related bilateral lower limb amputation (335 persons) were examined by two physicians for any history of genitourinary diseases and their documents were reviewed.   results: the mean age was...

Several studies have demonstrated that motor axons can discriminate between dorsally and ventrally derived muscles. In this paper we present evidence that (1) the pathway axons take in the limb constrain their access to either dorsally or ventrally derived muscles, and therefore (2) the axon's ability to discriminate between dorsal and ventral is expressed already at the level of pathway select...

Genetic variation in functionally integrated skeletal traits can be maintained over 10 million years despite bottlenecks and stringent selection. Here, we describe an analysis of the genetic architecture of the canid axial skeleton using populations of the Portuguese Water Dog Canis familiaris) and silver fox (Vulpes vulpes). Twenty-one skeletal metrics taken from radiographs of the forelimbs a...

The coordinated movement of the eyes and hands under visual guidance is an essential part of goal-directed behavior. Several cortical areas known to be involved in this process exchange projections with the dorsal aspect of the thalamic pulvinar nucleus, suggesting that this structure may play a central role in visuomotor behavior. Here, we used reversible inactivation to investigate the role o...

BACKGROUND Today a number of prosthetic suspension systems are available for transtibial amputees. Consideration of an appropriate suspension system can ensure that amputee's functional needs are satisfied. The higher the insight to suspension systems, the easier would be the selection for prosthetists. This review attempted to find scientific evidence pertaining to various transtibial suspensi...

Lower limb lymphedema is one of the common postoperative complications gynecologic malignancies, which brings great physical pain and psychological pressure to patients. In clinical treatment, Western medicine mainly based on conservative drug treatment surgery. Chinese "evidence" has various intervention methods, including internal external application medicine, acupuncture moxibustion, tui-na...

Background: Musculoskeletal disorders (MSDs) are among the most prevalent pains which could be ignited via material handling. Backpack wearers are among those who may carry heavy loads. Since MSDs mainly originate in school-aged children, students (as the largest group of backpack wearers) are considered more important. The purpose of this study is to design a backpack based on minimization of ...

Selection pressure for greater milk solid production, calving ease and early puberty attainment has resulted in the alteration of growth trajectory New Zealand dairy heifers. Although previous data have looked at stature terms height girth, changes as a result seasonal not been examined. In addition, relative contributions appendicular skeleton thorax relation to considered studies. Therefore, ...

Embodiment is the process by which patients with limb loss come to accept their peripheral device as a natural extension of self. However, there is little guidance as to how exacting the prosthesis must be in order for embodiment to take place: is it necessary for the prosthetic hand to look just like the absent hand? Here, we describe a protocol for testing whether an individual would select a...