N-RAP is a muscle-specific protein with an N-terminal LIM domain (LIM), C-terminal actin-binding super repeats homologous to nebulin (SR) and nebulin-related simple repeats (IB) in between the two. Based on biochemical data, immunofluorescence analysis of cultured embryonic chick cardiomyocytes and the targeting and phenotypic effects of these individual GFP-tagged regions of N-RAP, we proposed...

Databases Ee-Peng Lim, Meng-Liang Lim, Jaideep Srivastava Sch. of Applied Science, Nanyang Technological Univ. Nanyang Ave., Singapore 639798

Let σ1,σ2, · · · ,σn be positive real numbers satisfying n ∑ i=1 σi = 1 and A1,A2, · · · ,An be positive operators. Let Mσ,γ(A) = ( n ∑ i=1 σiA γ i ) 1/γ, γ > 0. It has been shown that lim γ→0+ Mσ,γ exists. Some known inequalities have also been generalized.

LIM-kinase 1 (LIMK1, where LIM is an acronym of the three gene products Lin-11, Isl-1 and Mec-3) is a serine/threonine kinase that phosphorylates cofilin and regulates actin cytoskeletal reorganization. LIMK1 contains two LIM domains and a PDZ (an acronym of the three proteins PSD-95, Dlg and ZO-1) domain in the N-terminal half and a kinase domain in the C-terminal half. In this study we examin...

Intermediate redshifts between galaxy surveys and the cosmic microwave background (CMB) remain unexplored territory. Line intensity mapping (LIM) offers a way to probe $z\gtrsim 1$ Universe, including epoch of reionization dark ages. Via exact nulling lensing kernel, we show that LIM lensing, in combination with (resp., CMB) can uniquely pre-reionization) Universe. However, foregrounds are key ...

On November 8, 2013, the Leaders in Medicine (LIM) program hosted the 5th Annual Research Symposium. Dr. Jerrold Ellner, Chief of the Infectious Diseases section at Boston Medical Centre and Professor of Medicine at Boston University School of Medicine, was the keynote speaker and presented his lecture entitled “Tuberculosis – Past, Present and Future”. The LIM symposium gives a forum for LIM a...

Lasp-2 binds to actin filaments and concentrates in the actin bundles of filopodia and lamellipodia in neural cells and focal adhesions in fibroblastic cells. Lasp-2 has three structural regions: a LIM domain, a nebulin-repeat region, and an SH3 domain; however, the region(s) responsible for its interactions with actin filaments and focal adhesions are still unclear. In this study, we revealed ...

The developmental activity of LIM homeodomain transcription factors (LIM-HDs) is critically controlled by LIM domain-interacting cofactors of LIM-HDs (CLIM, also known as NLI or LDB). CLIM cofactors associate with single-stranded DNA binding proteins (SSDPs, also known as SSBPs) thereby recruiting SSDP1 and/or SSDP2 to LIM-HD/CLIM complexes. Although evidence has been presented that SSDPs are i...

The aim of this paper is to prove the following results: a continuous map f : [0, 1]→ [0, 1] is chaotic iff the shift map σf : lim ← ([0, 1], f)→ lim ← ([0, 1], f) is chaotic. However, this result fails, in general, for arbitrary compact metric spaces. σf : lim ← ([0, 1], f) → lim ← ([0, 1], f) is chaotic iff there exists an increasing sequence of positive integers A such that the topological s...

We study model theoretical stability for Banach spaces and structures based on Banach spaces, e.g., Banach lattices or C∗-algebras. We prove that a theory is stable if and only if the following condition is true in every model E of the theory: If (ām ) and (b̄n) are bounded sequences in Ek and El (respectively) and R : Ek × El → R is definable, then there exist subsequences (āmi ) and (b̄n j ) su...