We studied 19 cases of proven/probable mucormycosis diagnosed from 2007 to 2015 in our hospital and assessed the microbiological characteristics of the isolates. We recorded the incidence of mucormycosis and clinical and microbiological data of infected patients. Isolates were identified to molecular level and tested for their antifungal susceptibility to azoles, amphotericin B, and liposomal a...

During 2016–17, 277 samples of leaf compost, manure, virgin and rhizosphere soil of some plants from Fars and Khuzestan provinces (Iran) were transferred to Mycology Laboratory of the Department of Plant Protection, Shiraz University (Iran). Fungi were recovered by soil plate and soil dilution methods. After purification, the isolates of Mucorales were identified based on growth, morphological ...

Six new N-substituted di- and tributyltin 2-aminoethanethiolates (cysteaminates) have been prepared and characterised by (1)H, (13)C and (119)Sn NMR spectroscopy. All these compounds exhibit a good in vitro antifungal effect against selected types of human pathogenic fungi (Candida albicans, Candida krusei, Candida tropicalis, Candida glabrata, Trichosporon beigelii, Aspergillus fumigatus, Absi...

Pulmonary mucormycosis (PM) is a life-threatening fungal infection in patients with hematologic malignancies, and early and accurate diagnostic modalities are urgently needed. We conducted a polymerase chain reaction (PCR) assay targeting these fungi in peripheral blood from four patients with hematologic malignancies who were strongly suspected of having PM. In these four patients, the Rhizopu...

The comparative virulence of six different strains of Absidia corymbifera for cortisone-treated and untreated Swiss mice was determined. Spores of the six strains were inoculated into mice by the intravenous, intraperitoneal, and intranasal routes. All six strains were found to be virulent in cortisone-treated and untreated mice by the intravenous route. Up to a 16-fold difference in strain vir...

Transformation of fungi by complementation of auxotrophs is generally much more reliable than usage of antibiotic resistance markers. In order to establish such a system for the model zygomycete Absidia glauca, a stable methionine auxotrophic mutant was isolated after X-ray mutagenesis of the minus mating type and characterized at the molecular level. The mutant is disrupted in the coding regio...

The hydroxylation of dehydroepiandrosterone (DHEA) to 7? -hydroxy-5-androstene-17-one (7?-OH-DHEA) and 7?-hydroxy-5-androstene-17-one (7?-OH-DHEA) by Gibberella sp. CICC 2498 Absidia coerulea 41050 was investigated. media ingredients were optimized. Single factors such as the DHEA concentration, culture time, medium volume, inoculum rate individually investigated generate optimum biotransformat...

The presence of molds in the environment around us can be beneficial or detrimental. Mold found various places, including soil, air, plants, animals, water, and on material surfaces. One roles mold is as a bio-degradator biodeterioration agent materials that are still used, so it will cause harm to humans. This study aims isolate characterize types exist surface existing biology laboratory Dipo...