We report a 60-year-old Caucasian female with a 2-year history of diffused granuloma annulare (GA), who presented for the simultaneous occurrence of genital lichen sclerosus (LS) and autoimmune thyroiditis (AT). In our opinion this combination is not just coincidental but may share similar immunopathological mechanisms.

These guidelines for the management of lichen sclerosus have been prepared for dermatologists on behalf of the British Association of Dermatologists. They present evidence-based guidance for treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, and a brief overview of epidemiological aspects, diagnosis and investigation.

Lichen sclerosus (LS) is a chronic inflammatory skin disease of unclear etiology in which lymphocytes play an important role. There is some evidence that LS is an autoimmune disease. The lesions are observed on mucosa areas in many cases in women genital region and on the skin of any part of the body. We report a case of a 54-year-old man. The single, inflamed lesion was situated in the scapula...

OBJECTIVE To collect and review all cases of sclerodermatous chronic graft-vs-host disease from January 1, 1982, through December 31, 2000. SETTING University hospital in Madrid, Spain. PATIENTS During the study period, 493 allogenic bone marrow transplantations were performed. Sclerotic lesions developed in 17 patients. RESULTS Sclerotic lesions appeared after a mean of 529 days. Previou...

OBJECTIVE To assess the current etiology, features, and natural history of urethral stricture disease in the developed world. MATERIALS AND METHODS We analyzed the data from 1439 male patients with urethral stricture, who had undergone surgical treatment in our referral urethral center from 2000 to 2010. The preoperative evaluation included a detailed clinical history of stricture, uroflowmet...

espanolEl liquen escleroso es una enfermedad inflamatoria cronica, de etiologia desconocida, que afecta la piel y las mucosas. Presentamos un caso paciente con genital extragenital concomitante, presento buena respuesta al tratamiento clobetasol tracrolimus topico en region genital, fototerapia ultravioleta B banda angosta (UVB-BA) lesiones extragenitales. EnglishLichen sclerosus is a chronic i...