Lichen planus is a T-cell mediated autoimmune disorder affecting the skin and mucous membranes. Ulcerating lichen planus is uncommon mostly on oral and genital mucosa but not skin. Lichen planopilaris, however, is a subtype of lichen planus affection hair follicles and leading to permanent scarring alopecia. We report a case of lichen planopilaris of the scalp with multiple alopecic patches ulc...

In the last few years there has been a special interest in the definition and classification of so called “premalignant oral diseases” (1). Frequent and controversial processes such as oral lichen planus and other similar oral lesions are included in this group (2, 3). Oral lichen planus is clinically characterized by white papular lineal lesions which show a reticular pattern, associated or no...

background and aims. the role of cytokines in the immunopathogenesis of oral lichen planus (olp) has received much attention. the aim of this study was to evaluate the serum levels of tnf-α and tgf-β in patients with olp in an iranian population. materials and methods. thirty-two patients with olp and 32 age-matched healthy volunteers as a control group were included in this study. serum tests ...

background and aims. lichen planus is a relatively common mucocutaneous disease, with an unknown etiology. there is no complete cure for oral lichen planus (olp), but some drugs, including corticosteroids, retinoids, cyclosporine and antibiotics are commonly used for treatment of olp. the aim of the present study was to compare the effect of combination of triamcinolone and vitamin a mouthwash ...

unstimulated whole salivary p53 was evaluated in non-involved subjects, in patients suffering from oral lichen planus (olp) and squamous cell carcinoma (scc). a total of 34 patients with olp, 24 patients suffering from oral scc and 41 non-involved participants were enrolled. the unstimulated whole saliva p53 level was assayed by elisa. data was analyzed by anova followed by the tukey post hoc t...

background: the association between oral lichen planus (olp) as a common oral disease and hcv infection as an etiological factor in the development of hepatocellular carcinoma has been widely reported. however, there are wide geographical variations in the reported prevalence. this study was performed to determine the prevalence of l. planus in hcv+ patients in shiraz, southern iran. â  methods...

background oral lichen planus (olp) is a chronic inflammatory disease affecting the oral mucosa in 0.5-2% of the world’s population. it is more common in women compared to men and the mean age at the onset of the lesion is the fourth decade. objectives the purpose of this study was to evaluate the presence of helicobacter pylori (h. pylori) in oral lichen planus and oral lichenoid reaction. mat...

BACKGROUND & OBJECTIVE Lichen planus is a mucocutaneous disease which is relatively common and in 30-70% of patients, mucosal lesions can be seen and known as a precancerous lesion but its etiology is not completely understood. Desmogleins I and III are the main desmosomal transmembrane proteins. These proteins have been identified as the autoantigen of the autoimmune disease. The aim of this s...

background: proliferating cell nuclear antigen (pcna) is a nuclear protein synthesized in the late g1 and s-phase of the cell cycle. detection of this protein represents a useful marker of the proliferation status of lesions. this study has been carried out to evaluate the cell proliferation rate in oral lichen planus (olp) and comparison between plaque and erosive lichen planus, which indicate...