Sertoli-Leydig cell tumours are uncommon tumours comprising less than 0.5% of ovarian neoplasms. It is a sex cord stromal tumour. As the name indicates, Sertoli-Leydig cell tumours are composed of a mixture of variable proportions of cells morphologically resembling male Sertoli and Leydig cells. Most tumours are unilateral and confined to ovaries. And they are seen during the second and third ...

Sertoli leydig cell tumors are exceedingly uncommon tumors of the ovary accounting for less than 0.5% of all ovarian neoplasms and 1% of sex cord tumors. These tumors are functional and secrete testosterone and only rarely they are estrogenic. Hence the patients present with virilization features. Most of the tumors are unilateral and bilaterality is extremely rare. Here we report an unusual ca...

The tumor microenvironment (TME) is a complex environment composed of variety stromal cells and immune that infiltrate the space. Recent clinical work has shown intratumoral cell infiltration.

objective(s) this investigation was conducted to evaluate the effects of diabetes on the structure and function of testicular tissue. materials and methods diabetes was induced in male adult rats by a single intraperitoneal injection of streptozotocin. body and testicular weight, hormonal analyses, histological and ultrastructural analyses were measured. results the body and testicular weights ...

desmoplastic ameloblastoma is a rare variant of ameloblastoma. up until now, less than 150 patients have been reported in the literature. we report a case of desmoplastic ameloblastoma in a 45-year-old female with a painless swelling in the left anterior maxillary region. fine needle aspiration yielded no fluid. periapical and panoramic radiographs as well as computer tomography scan showed a m...

gastrointestinal stromal tumors (gists) are rare and these tumors are mesenchymal tumors that develop in the wall of the gi tract. the aim of this study was to report a case with gist in pregnancy in western iran. a 39-year-old pregnant female (g5 p4) was admitted with a chief complaint of abdominal pain and epigastric fullness on 12 th april 2016. sonography showed gestational age of 15w+1d an...

Sertoli cell tumor, also termed androblastoma or gonadal stromal tumor, is a rare testicular neoplasm. While it is usually benign, 25 cases of malignant Sertoli cell tumors have been reported.'" These neoplasms vary greatly in microscopic appearance and unfortunately they have aggressive metastatic behavior. Despite various treatments, the prognosis remains poor. We report on the fourth prepube...

Calcifying fibrous tumor (CFT) is a rare mesenchymal tumor, affecting children and young adults with a predilection for the soft tissue and the abdominal cavity. CFT of the tubular gastrointestinal tract is very rare with less than 20 cases of gastric CFTs reported in English literature. This benign hypocellular fibrosclerotic calcifying lesion can resemble other spindle cell tumors particularl...

The child with testicular enlargement in the absence of gonadotrophin stimulation presents a difficult diagnostic dilemma. Leydig cell tumors, Leydig cell hyperplasia, and tumors of adrenal rest tissue are the primary etiologic considerations. Because of considerable overlap in clinical presentation, careful biochemical and histologic evaluations are necessary to make the diagnosis. These shoul...