the identification of early markers of atopy in cord blood of newborns at delivery may offer prediction of future allergic sensitization. the aim of this study was to evaluate the relationship between cord blood interleukin-13 (il-13) and interferon-gamma (ifn-γ) and development of allergic diseases during the first five years of life. umbilical cord blood samples were collected at the time of ...

hla-g is normally expressed on human trophoblast cells. it is a non-classical mhc molecule class i b. the role of hla-g in diabetic type 1 is not known. we investigated the role of ifn-β in induction hla-g expression on the monocyte derived dendritic cells (dc) in diabetes type 1. treatment of dendritic cell with ifn-β in vitro from diabetic patients (n=20) and normal subjects (n=20) resulted t...

promoter polymorphism of cytokine genes may lead to inter-individual differences in cytokine levels, therefore, polymorphisms may associate with susceptibility to infectious diseases. in this study, we investigated a possible association between interleukin-10 (il-10) -1082a⁄g (rs1800896) and interferon (ifn)-gamma +874t/a (rs2430561) promoter polymorphisms and tuberculosis (tb) in the azeri po...

objective(s): the effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study.   materials and methods: male wistar rats were randomly divided into control sedentary (c), moderate trained (mt), (v=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (ot) (v=25 m/min, 60min/day for 6 days a week, 11 weeks) and recovered overtrained (or)...

background: the effect of low dose radiation on immune system is shown. ionizing radiation can affect cytokine production and polarization of t helper cells. objective: the current study focused on ionizing radiation in ukrainian children residing in a contaminated area with clinical irritable bowel syndrome. method: our study included 75 rural children population aged 4-18 yrs, who lived in a ...

background macrophages play critical roles in innate immune response in the liver. whether macrophages participate in liver innate immunity against hcv replication is poorly understood objectives the aim of this study was to investigate the role of macrophages in liver innate immunity against hcv replication. conclusions macrophages may play an important role in liver innate immunity against hc...

Background : Allergic asthma is a chronic inflammatory disease of airway that often determined with degrees of inflammation, hypersensitivity, bronchial constriction and airway changes. Th1, Th2 and Th17 cells are the main cells involved in the pathophysiology of asthma. . Therefore, this study evaluated Th1, Th2, and Th17 cells functions by assessment the expression of INF-g, IL-4, and IL-17 g...