نتایج جستجو برای: leukocyte telomere length

تعداد نتایج: 346584  

Journal: :The Journal of Clinical Endocrinology & Metabolism 2011

2016
Jih-Kai Yeh Chao-Yung Wang

Telomeres are tandem repeat DNA sequences present at the ends of each eukaryotic chromosome to stabilize the genome structure integrity. Telomere lengths progressively shorten with each cell division. Inflammation and oxidative stress, which are implicated as major mechanisms underlying cardiovascular diseases, increase the rate of telomere shortening and lead to cellular senescence. In clinica...

Journal: :Neuro endocrinology letters 2016
Dana Dlouha Jevgenija Vymetalova Ivan Malek Jaroslav A Hubacek

OBJECTIVES Telomeres are repetitive non-coding DNA sequences on the ends of eukaryotic chromosomes. Relative leukocyte telomere length (LrTL) is considered to reflect biological ageing and fitness. Therefore, we examined whether LrTL would reflect rTL in aortic tissue (ArTL) and whether it could be used as a marker of biological heart age. DESIGN We analysed telomere length in aortic and leuk...

Journal: :Cancer Epidemiology Biomarkers & Prevention 2007

Journal: :The Journal of Clinical Endocrinology & Metabolism 2019

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