نتایج جستجو برای: leukemia inhibitory factor

تعداد نتایج: 1179185  

Journal: :The Journal of Experimental Medicine 1995
D Chauhan S M Kharbanda A Ogata M Urashima D Frank N Malik D W Kufe K C Anderson

Oncostatin M (OSM) is a 28-kD glycoprotein recently identified as a growth factor for human multiple myeloma cells. It belongs to a family of distantly related cytokines that includes interleukin 6, ciliary neurotrophic factor, leukemia-inhibitory factor, and interleukin 11. These cytokines initiate signaling by inducing either homodimerization of gp130 or heterodimerization of gp130 with leuke...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2016
Eric Solary

The proliferative component of chronic myelomonocytic leukemia, related to an increased sensitivity of myeloid progenitors to granulocyte macrophage-colony stimulating factor, suggests dedicated therapeutic approaches. In this issue, ruxolitinib, a JAK1 and -2 inhibitory drug, is shown to induce objective responses in chronic myelomonocytic leukemia patients. Clin Cancer Res; 22(15); 3707-9. ©2...

 محمد اکبری, , علیقلی سبحانی, , قاسم ساکی, ,

Background: This study was performed to investigate the rate of inner cell mass of blastocyst which obtain from culture of mouse two cell embryos in presence and absence of recombinant of human leukemia inhibitory factor. Materials and Methods: ICR female mice that were between 6-8 weeks old received intra peritoneal injection of 7.5 IU of pregnant mare serum gonadotropine for super ovulati...

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