CONTEXT Leptospirosis is an emerging zoonosis world wide; it is being reported in many areas of south-east Asia now. A recent surge in the number of patients with leptospirosis has been noted in the Sub-Himalayan region of North India which was uncommon. We present here a case series of 13 patients who were positive for leptospirosis either by IgM Elisa or PCR method. AIMS To study the profil...

The prevalence of leptospirosis in Sri Lanka has gradually increased since the earliest reports in 1953 [1]. Statistics show that in 2007 about 10% of medical ICU admissions were due to leptospirosis, and 65% of them died from complications. Regular evaluation of the clinical features of leptospirosis is important for early detection and accurate management of the disease [1]. The objective of ...

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Cardiac disturbances are relatively common and electrocardiographic abnormalities may be found in more than 70% of patients with leptospirosis. We report the case of a 68 year-old male with severe leptospirosis who developed atrial flutter. Effective treatment was done with amiodarone. The patient became clinical stable, with complete recovery. Rigorous clinical observation and continuous elect...

Leptospirosis is an emerging infectious disease with worldwide distribution.[1] It is endemic in most tropical and subtropical countries. In Sri Lanka, leptospirosis is a notiÞ able disease and around 1500 cases are reported annually to the epidemiology unit.[2] Almost all the cases are reported on clinical suspicion without laboratory conÞ rmation.[3] Seroepidemiological data on leptospirosis ...

BACKGROUND In Western countries, leptospirosis is uncommon and mainly occurs in farmers and individuals indulging in water-related activities. In tropical countries, leptospirosis can be up to 1000 times more frequent and risk factors for this often severe disease may differ. METHODS We conducted a one-year population-based matched case-control study to investigate the frequency and associate...

Leptospirosis is a re-emerging infectious disease affecting both animals and humans worldwide. This infection is associated with occupational contact with animals, recreational exposure and contact with leptospires as a consequence of flooding. Multiple organ involvement may be encountered in acute severe leptospirosis and early renal involvement is commonly characterized by tubulo-interstitial...

INTRODUCTION leptospirosis is a zoonosis of worldwide importance. The disease is endemic in Brazil. This study was conducted to describe the clinical and laboratory presentation of leptospirosis in a metropolitan city of Brazil. METHODS this is a retrospective study including 201 consecutive patients with leptospirosis admitted to tertiary hospitals in Fortaleza, Brazil, between 1985 and 2006...

The reported incidence of leptospirosis increased 30-fold in Thailand between 1995 and 2000. Despite many hypotheses to explain the increase, the true etiology remains unknown. We conducted a review of the national surveillance system for leptospirosis, examining the reporting practices, system attributes, and utilization of laboratory confirmation in two northeastern provinces. Using standard ...

Early detection of leptospirosis with field-ready diagnostics may improve clinical management and mitigate outbreaks. We previously validated the point-of-care Dual Path Platform (DPP) for leptospirosis with sera in the laboratory. This prospective study compares the diagnostic accuracy and clinical utility of the DPP using finger stick blood (FSB) against the serum DPP, venous whole blood (VWB...