Background: Just like diabetes, leprosy also cause painless neuropathic ulcers which process is mediated by Schwann-cell. Biochemical changes on patients presumed to have role pathogenesis of diabetes mellitus. Methods: This study cross-sectional aimed know further about diabetic status population people affected leprosy, as the preliminary prove association between mellitus and leprosy. Data, ...

We observed 29 patients presenting with vague peripheral neurological symptoms for 6 months or more. During this period, 16 developed clinical leprosy, 3 developed borderline tuberculoid leprosy and the other 13 developed neuritic leprosy. Of these 13 cases 11 subsequently developed skin lesions similar to those seen in indeterminate and in borderline tuberculoid leprosy. Based on the above obs...

Serum levels of soluble tumor necrosis factor alpha receptor I (sTNF-RI) were elevated in patients with lepromatous (LL) reactional-state type II leprosy, and sTNF-RII levels were increased in patients with full tuberculoid (TT) or LL type II leprosy. The sTNF-R in sera from patients with type II leprosy, but not other forms of leprosy, inhibited recombinant TNF cytolytic activities in vitro. T...

Since the onset of COVID-19 pandemic, priorities leprosy affected patients in seeking anti-leprosy treatment have been affected. This study was initiated at a tertiary hospital India to understand health behaviour who delayed their treatment. A total 164 during lockdown were recruited. The and methods adopted by retrospectively analysed through an exploratory study. Lockdown prevented travel ma...

Leprosy is of big concern in the medical fraternity. also known as Hansen’s disease. It a curable communicable disease that remains prevalent most countries all over globe. chronic granulomatous infection commonly caused by Mycobacterium leprae and lepromatosis, which mainly show an effect on skin peripheral nerves. To control minimize impact disease, much effort has been put into it for decade...

Leprosy is a slow, chronic disease with a long incubation period caused byMycobacterium leprae. The clinical presentation varies across a wide spectrum from tuberculoid to lepromatous leprosy. The condition is characterized by skin lesions and damage to peripheral nerves leading to physical disability and social problems. The past 50–60 years have witnessed remarkable progress in the fight agai...

From whatever standpoint leprosy is viewed, whether from that of the clinician or the epidemiologist, the objective must be to diagnose and treat the maximum number of leprosy patients, not only because the disease is curable but because treatment renders ' open ' cases non-contagious long before cure is obtained. Now that it is becoming generally accepted that the way to leprosy eradication li...

Background Leprosy is a chronic infectious disease with permanent complications that mainly affect the skin, peripheral nerves, mucosal surfaces of the upper respiratory tract, and eyes. The aim of this study was to investigate the epidemiology and trends of leprosy in Iran from 2005 to 2015. Materials and Methods This was a cross-sectional study analyzing leprosy records from the Center for ...

In northern Nigeria 60 leprosy patients, 49 outpatients and 11 in-patients, were interviewed about their help-seeking behaviour and explanatory models before their first contact with the leprosy services. Most patients showed a delay of more than 1 year. After leprosy was provisionally diagnosed by lay persons, 27% of patients found their way to the leprosy services within 3 months. Chemists (p...

Recently, in line with the target date of the global Millennium Development Goals (MDG-6), WHO has proposed an ‘enhanced global strategy’ to sustain leprosy control and to further reduce the global burden of leprosy by 2015. The thrust of achieving the goal of ‘elimination’ of leprosy as a public health problem at national level by the Government of India (GOI) has changed forever the method of...