BACKGROUND Approximately 3.5 million U.S. schoolchildren are limited in English proficiency (LEP). Disparities in children's health and health care are associated with both LEP and speaking a language other than English at home, but prior research has not examined which of these two measures of language barriers is most useful in examining health care disparities. OBJECTIVES Our objectives we...

BACKGROUND Preclinical studies comparing paclitaxel formulated with polyethoxylated castor oil with the sonicated formulation of liposome-entrapped paclitaxel (LEP) have demonstrated that LEP was associated with reduced toxicity while maintaining similar efficacy. Preliminary studies on the pharmacokinetics in patients support earlier preclinical data, which suggested that the LEP Easy-to-Use (...

Leprosy is a chronic infectious disease that may present different clinical forms according to the immune response of the host. Levels of IFN-γ are significantly raised in paucibacillary tuberculoid (T-lep) when compared with multibacillary lepromatous (L-lep) patients. IFN-γ primes macrophages for inflammatory activation and induces the autophagy antimicrobial mechanism. The involvement of aut...

Moths were collected from different parts of Peshawar during June to August in 2007 to determine their diversity, species richness and evenness. A total number of 774 moth specimens were collected by using simple light traps operated from dusk to dawn daily for sixty nights. The moths caught were identified up to family level. Families Noctuidae, Pyralidae, Arctiidae, Geometridae, Sphingidae an...

Neural sites that interact with the suprachiasmatic nuclei (SCN) to generate rhythms of unrestricted feeding remain unknown. We used the targeted toxin, leptin conjugated to saporin (Lep-SAP), to examine the importance of leptin receptor-B (LepR-B)-expressing neurons in the arcuate nucleus (Arc) for generation of circadian feeding rhythms. Rats given Arc Lep-SAP injections were initially hyperp...

We review the results of the Standard Model Higgs boson search at LEP. An emphasis is put on revealing the details behind the statistical procedure developed by the LEP Higgs working group. The procedure is explained using a toy model which allows the reader to estimate the significance of the experimental observation which led at the time to a scientific debate on whether LEP has observed a 11...

The aim of this study was to analyze LEP and DGAT1 gene polymorphisms in 3 Nelore lines selected for growth and to evaluate their effects on growth and carcass traits. Traits analyzed were birth, weaning, and yearling weight, rump height, LM area, backfat thickness, and rump fat thickness obtained by ultrasound. Two SNP in the LEP gene [LEP 1620(A/G) and LEP 305(T/C)] and the K232A mutation in ...

Measurements made by the four LEP experiments of electroweak parameters and the strong couphng constant are presented. These are used in an overaU Standard Model fit and a constraint on the mass of the top quark is derived. 1. Precision Measurements of Electroweak Parameters During 1989, 1990 and 1991 the four main experiments at the LEP e+ecollider (ALEPH, DELPHI, L3 and OPAL) have recorded da...

Obesity is a public health problem that increases the risk of metabolic disease, infertility, and other chronic health problems. The present study aimed to develop a new rat model for sex hormone disorder with overweight and Ca loss by intramuscular injection of exogenous leptin (LEP). Thirty female Sprague-Dawley (SD) rats (40 days old) were injected thrice intramuscularly with LEP or keyhole ...

Variants in leptin gene (LEP) have been implicated in the pathogenesis of obesity. The relationship between LEP G-2548A polymorphism and obesity-related traits was evaluated in a sample of Brazilian women (n = 228) who were randomly selected from two clinical centers in Sao Paulo city. Blood samples were collected for DNA extraction, plasma leptin and serum lipids measurements. LEP G-2548A geno...