Assessment of myocardial viability 1>rior to revascularization procedures is an important clinical consideration for improved functional recovery of regional left ventricular dysfunction. In chronic coronary artery disease, impaired left ventricular function , at least in part, is due to ischemic or hibernating myocardium rather than just myocardial fibrosis. Functional recovery of the left ven...

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by ventricular arrhythmias and fibrofatty replacement of the right ventricular (RV) myocardium. Although the RV is the predominant chamber involved, left ventricular (LV) involvement has also been documented. Electrophysiological correlations of histopathologic findings in nonischemic cardiomyopathy, and especially in ARVC,...

The mammalian heart develops from a primary heart tube, which is formed by fusion of bilateral cardiac territories in which myocardial and endothelial cells have already begun to differentiate from splanchnic mesoderm. A population of myocardial precursors has been identified in pharyngeal mesoderm, anterior to the early heart tube. Cell labeling studies have indicated that this novel territory...

Objective Non-viable myocardium can be detected using the late enhancement magnetic resonance imaging (MRI) technique [1]. Recently, T2weighted MRI scans of myocardial edema representing the area at risk in acute myocardial infarction has been introduced [2]. To improve visualization of edematous or hyperenhanced myocardium, blood is often nulled employing black-blood techniques such as a dual-...

This study investigated the effects of Ligusticum wallichii on IL-1β expression in myocardium and central nervous system after AMI. AMI rat was administrated with Ligusticum wallichii extract. A series of assays were used to detect the effects of Ligusticum wallichii extract on infarct size, left ventricular ejection fraction, expression of TLR-4, NF-κB, and IL-1β in myocardium, IL-1β expressio...

An asymptomatic 5-year-old girl presented with bradycardia during a routine well-child visit. Further evaluation revealed profound sinus bradycardia, exercise-induced bidirectional ventricular tachycardia, and supraventricular tachycardia. An echocardiogram showed heavy trabeculations in the left ventricular myocardium. This patient's presentation suggested catecholaminergic polymorphic ventric...

In patients with heart failure, decreased contractility resulting in high end-diastolic pressures and a restrictive pattern of left ventricular filling produces a decrease in early diastolic filling, suggesting a stiff ventricle. This study investigated the elastic properties of the myocardium and left ventricular chamber and the ability of the heart to utilize elastic recoil to facilitate fill...

THAT THE catechol amines or cardiac sympathetic nerve stimulation will increase the vigor of ventricular contraction has been established." Further, it is now known that the ventricle will contract more forcefully from any given filling pressure under these influences." The early studies of Anrep and other more recent studies" indicate that a changed myocardial extensibility cannot, of itself, ...

BACKGROUND The uptake of F-18 deoxyglucose into dysfunction segments after myocardial infarction identifies metabolically active (FDG+) or inactive (FDG-) myocardium. Although patients with FDG+ segments have been found to be at risk for adverse events, the prognostic significance of viable myocardium in relation to other influences on postinfarction prognosis, including revascularization, rema...