The effect of nifedipine on left ventricular isovolumic relaxation and diastolic filling properties and systemic and left ventricular hemodynamics was studied in 15 patients with hypertrophic cardiomyopathy. After nidefipine (10 mg sublingually), the prolonged left ventricular isovolumic relaxation time assessed by echocardiography decreased from 112 +/- 26 to 83 +/- 23 msec (p less than 0.0001...

BACKGROUND The transmitral E wave and the peak velocity of early diastolic mitral annular motion (e`) both decrease with age, but the mechanisms underlying these age-related changes are incompletely understood. This study investigated the possible contributions of blood pressure (BP) and left ventricular end-diastolic length (LVEDL) to age-related reductions in E and e`. METHODS The study gro...

Thirteen patients with severe chronic aortic regurgitation (mean age 52.5 years) were studied by serial M-mode echocardiography. When first studied, none had breathlessness caused by left ventricular failure (LVF). Nine of these patients remained asymptomatic over a mean period of 4 years, 3 months (no LVF group); the other four patients developed left ventricular failure with dyspnea after a m...

Objective: To investigate the effect of sacubitril-valsartan combined with Zhenyuan capsule in treatment chronic heart failure comorbid anxiety and depression its on level inflammatory factors. Methods: A total 106 patients from February 2020 to March 2022 were continuously enrolled divided into control group (36 cases), observation cases) B (34 according methods. All groups given conventional ...

BACKGROUND Evaluation of myocardial function is clinically challenging in dogs with degenerative mitral valve disease (DMVD). Although myocardial dysfunction is caused by pathologic degeneration, histopathologic progression is poorly understood. OBJECTIVES To characterize myocardial and pulmonary pathologic changes according to severity in dogs with naturally occurring DMVD, and to investigat...

BACKGROUND In some patients with nonischemic idiopathic dilated cardiomyopathy (DCM), left ventricular (LV) dysfunction improves spontaneously but can recur. The factors predicting recurrence of LV dysfunction in recovered idiopathic DCM are poorly defined. We investigated the clinical, echocardiographic, and laboratory variables affecting recurrence of LV dysfunction in patients who recovered ...

OBJECTIVES The aim of this study was to determine if left ventricular preload, afterload or contractility is a correlate of left ventricular mass index in hypertensive pediatric patients. BACKGROUND It is believed that decreased contractility and increased preload are associated with left ventricular hypertrophy in adult hypertensive patients. METHODS Ninety pediatric hypertensive patients ...

Symptoms of congestive heart failure frequently reflect abnormalities in both systolic and diastolic performance. While much work has been reported regarding the mechanisms by which positive inotropic and vasodilator therapy affect systolic performance, little is known about their effect on diastolic function. In 12 patients with diffuse congestive cardiomyopathy micromanometer left ventricular...

PURPOSE To determine whether 3.0-T magnetic resonance imaging (MRI) could assess right ventricular (RV) function in patients with hypertrophic cardiomyopathy (HCM), and if this assessment is correlated with the New York Heart Function Assessment (NYHA) classification. MATERIALS AND METHODS Forty-six patients with HCM and 23 normal individuals were recruited. Left and right ventricular functio...

Objective: This study aims to analyze the diagnostic value of echocardiography in patients with chronic heartfailure. Methods: 30 heart failure admitted our hospital during January 2021 2023 were selected as observation group, and healthy people who received physical examination same period reference group. Both groups echocardiography, results ultrasound compared, subjects group grouped accord...