PURPOSE: We studied the effects of exposure to mitomycin C and 5-Fluorcuracil to human RPE cultures, in growth inhibition and citoxicity. METHODS: 1) Growth inhibition: RPE cultures (3.000 cells/well) were exposed to different concentrations of mitomycin C and 5-Fluorouracil, and cell viability (MTT test) was evaluated 48h, 72h and 96h after. 2) Citotoxicity: RPE cultures (10.000 cells/well) we...

abstract heavy metals are the important pollution which there is in the aquatic ecosystems. today, with advances in technology have increased the pollution therefore it is important to assessment the risks. the aim of this study was acute toxicity effects of mercury chloride, lead chloride and zinc chloride in silver carp fish. in this study there were 5 treatments for lead chloride and mercury...

Background: The presence of pesticides is very prevalent in surface waters of Iran due to their huge consumption for agricultural purpose. These toxic substances may accumulate in the food chain and cause serious ecological and health problems. Chemical pesticides with persistent molecules (long half-life periods) pose a threat to aquatic life forms and the human population consuming the affe...

The aim of this study was utilizing Kemin multi-enzyme in common carp (Cyprinus carpio) diet and investigating the impact on fish survival rate exposed to the lethal concentration of abamectin. For this purpose, 350 fish were divided into two experimental diets, containing 0 and 1000 mg Kemin kg-1 of diets for 6 weeks and weighed end of this stage. Then, LC50 of abamectin for fish dietary consu...

Different pollutants have undesirable effects on aquatic ecosystems, detergent powder is one of the elements in the sewages so study on the effects of this factor on  aquatic animals is crucial. The aim of the present study was to investigate acute effects of detergents as potentially dangerous additive to assess mortality effects of this product on some cultured fish. Silver Carp (Hypopht...

The toxicity of eight botanically based biopesticides was evaluated against third instars of the scarab larvae (Coleoptera: Scarabaeidae) Popillia japonica Newman, Rhizotrogus majalis (Razoumowsky), Anomala orientalis Waterhouse, and Cyclocephala borealis Arrow. Soil dip bioassays were used to obtain concentration-mortality data 7 d after treatment of larvae, leading to the calculation of LC50 ...

Dichloromethane and/or ethanol extracts of 30 plants used as traditional medicines in Bukoba district, northwestern Tanzania were evaluated for brine shrimp toxicity. Among the 50 extracts tested, 32 extracts (64%) showed very low toxicity with LC50 values above 100 microg/ml. Among these 12 (24%) which had LC50 >500 microg/ml can be categorized as being practically non-toxic. Among the remaini...