Aim. The objective was to evaluate the synergistic effects of fermented rice extracts (FRe) on the laxative and probiotic properties of yoghurt in rats with loperamide-induced constipation. Methods. After constipation induction, yoghurt containing FRe (BFRe; 0.05%, 0.1%, or 1%) was administered orally once per day for 6 days. Results. Loperamide treatment caused marked decreases in fecal pellet...

PURPOSE To investigate clinical, demographic and dietary factors associated with constipation in a sample of community dwelling people with Parkinson's disease, recruited through a specialist outpatient clinic. Partners/carers provided a convenience control group. SCOPE Participants completed a baseline questionnaire (background information, diet and exercise, activities of daily living: mobi...

BACKGROUND The present study was aimed to provide ethnopharmacological basis for the medicinal use of Viola betonicifolia whole plant in indigestion and constipation. METHODS Mice were used in in-vivo prokinetic and laxative studies while in-vitro experiments were conducted on isolated tissues of rabbit and guinea-pig gut preparations suspended in a tissue bath to measure isotonic contraction...

BACKGROUND Constipation is the most common gastrointestinal complaint all over the world and it is a risk factor of colorectal cancer. In this study, the efficacy of aqueous leaf extract of Aloe ferox Mill. was studied against loperamide-induced constipation in Wistar rats. METHODS Constipation was induced by oral administration of loperamide (3 mg/kg body weight) while the control rats recei...

Due to its laxative effects, senna (Cassia angustifolia) has been used frequently in our country and the whole world. We aimed to present a case in which a probable hepatotoxicity and death occurred because of senna used in large quantities for a long time due to its laxative effects. A sixty years old female patient admitted our emergency service with the complaints of weakness, abdominal pain...

A housewife, 40 years of age, was admitted with dysesthesia of the extremities, muscle weakness, and attacks of adynamia and thirst. She had been taking a laxative for more than 20 years. On physical examination, blood pressure was 94/56 mmHg. Laboratory tests revealed thrombocytosis, low serum K and marked increases in both plasma renin activity and serum aldosterone. Serum TBG was increased. ...

PURPOSE There is a scarcity of literature, and prevalent misconceptions about constipation in India. METHODS A literature search in PubMed was conducted with regard to epidemiology, clinical features, and management of constipation. Special emphasis was paid to functional constipation and refractory constipation. English language studies available full text over the last 25 years were conside...

Background: Colonoscopy is the preferred procedure for diagnosis of large-bowel diseases in dogs. Polyethylene glycol (PEG) is the most commonly used laxative for colonic cleansing. Senna has been used in traditional medicine as a laxative and an aid to treat constipation. OBJECTIVES: The aim of this study was to evaluate the safety of senna as an alternative or adjunct to polyethylene glycol s...

Globimetula braunii (Engle) Van Tiegh is a member of the Loranthaceae family. The family is represented by 65 genera and 900 species found in the tropics and are mainly distributed in Africa, Asia, Australia and South America (Johnri, 1987). G. braunii grows as a hemi-parasite on host trees such as Jatropha curcas, Citrus species and Cola species. It is commonly known as mistletoe and “Afomo On...