The birth and expansion of continental plateaus exert a strong control on our planet's climate the distribution evolution its biodiversity. It has been proposed that Tibetan Plateau steadily growing by southward expansion. Here we demonstrate shape southeastern margin plateau remained unchanged for last 10 Myr despite vast amounts exhumation. Our finding is based new, high-resolution thermochro...

objectives: the aim of this study was to assess and compare the characteristics of commonly used initial archwires by their load deflection graphs. materials and methods : this study tested three wire designs namely copper nickel titanium (cnt), nickel titanium (niti), and multi-strand niti (msnt) archwires engaged in passive self-ligating (psl) brackets, active self-ligating (asl) brackets or ...

Previous studies of postnatal synaptic development in human frontal cortex have shown that synaptic density rises after birth, reaches a plateau in childhood and then decreases to adult levels by late adolescence. A similar pattern has been seen in nonhuman primate cortex. These earlier studies in human cortex are limited, however, by significant age gaps in study subjects at critical inflectio...

[1] We show that time‐dependent models of mantle upwellings above a cold downwelling in the New Zealand‐Antarctica region since 80 Ma can explain anomalous geophysical observations: ∼1.0 km of positive residual bathymetry at the Antarctica margin, a large Ross Sea geoid low, 0.5–0.9 km of excess tectonic subsidence of the Campbell Plateau since 80 Ma, and several seismic wave speed anomalies. M...

Drug sensitivity and cell cycle parameters of L1210 cells in culture in exponential (10(5) to 4 x 10(5) cells/ml) and plateau phase (greater than 8 x 10(5) cells/ml) of growth were compared. The percentage of cells in G1, S, and G2 + M for exponential and plateau-phase cultures was 24.1, 70.0, and 5.9, and 42.5, 45.6, and 11.9, respectively. These values correspond to those reported previously ...

1 make an important contribution to our understanding of the physiological and pathophysiological roles of late sodium current (I Na) in the heart, with a focus on a key pathways regulating late I Na amplitude. They conducted well-designed and detailed studies with 2 new genetically engineered mouse lines: an S571A mouse that ablates phosphorylation by Ca 2+ /calmod-ulin-dependent kinase II (Ca...

Subtropical China harbours the world's most diverse temperate flora, but little is known about the roles of geographical and eco-climatic factors underlying the region's exceptionally high levels of species diversity and endemism. Here we address this key question by investigating the spatio-temporal and ecological processes of divergence within the Dysosma versipellis-pleiantha species complex...