the aim of this study is to determine whether there is a role of podoplanin and glutathione s-transferases t1 (gst-t1) expression in laryngeal squamous cell carcinoma. the study was completed with 33 patients and gene expression analysis was performed by qrt–pcr. the podoplanin and gst-t1 expression patterns were analyzed to determine their correlation with clinicopathologic parameters of laryn...

laryngeal leiomysarcoma is an extremely rare malignancy originating from smooth muscle cells. its rarity is due to the fact that only less than 50 cases of pure laryngeal leiomyosarcoma and less than 10 cases of hypopharyngeal leiomyosarcaoma have been reported in modern medical literature.  even though the clinical presentation mimics that of a laryngeal carcinoma forming the major bulk of the...

OBJECTIVE To determine the differences in myelination between the human recurrent laryngeal nerve and superior laryngeal nerve. METHODS Fifteen confirmed laryngeal nerve specimens were harvested from five cadavers. Cross-sections were examined under a photomicroscope and morphometric analysis performed. RESULTS There was a significantly greater number of myelinated fibres than unmyelinated ...

following the first report of laryngeal small cell carcinoma in canada in 1972,only 82 cases of this cancer has been reported in the literature untill 2001.this cancer originates from laryngeal neuroendocrine cells.It,s clinical presentation consists of hoarseness,breathing difficulty:and cigarette smoking is the most important risk factor.this type of cancer is mostly presented after 50 years ...

BACKGROUND The purpose of this study was to evaluate the contribution of laryngeal intraoperative nerve monitoring (IONM) during thyroidectomy in predicting postoperative laryngeal mobility. METHODS Between 2009 and 2012, 127 patients underwent thyroidectomy, during which 216 recurrent laryngeal nerves were stimulated with suprathreshold stimulations. Laryngeal mobility was examined through d...

Laryngeal schwannomas are rare, benign tumors, most often arising from the superior laryngeal nerve. We describe a case of a 68-year-old female with a laryngeal schwannoma of the recurrent laryngeal nerve after traumatic injury. We postulate that trauma to the recurrent laryngeal nerve during thyroidectomy or thyroplasty incited growth of a nerve sheath tumor. This is the first reported case of...

Tsai, Tung-Lung, Shyue-Yih Chang, Chin-Yin Ho, and Yu Ru Kou. Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats. J Appl Physiol 101: 328 –338, 2006; doi:10.1152/japplphysiol.00064.2006.—Laryngopharyngeal or gastroesophageal reflux is associated with laryngeal airway hyperreactivity (LAH), but neither t...

We have improved the ArtiSynth biomechanical modeling toolkit to meet new challenges in oral, pharyngeal and laryngeal modeling. Our team’s current research efforts have focused on four important developments: 1. patient specific modeling, 2. updating the ArtiSynth simulation engine to support integrated soft and hard tissue models, 3. inverse modeling techniques and 4. computational fluid dyna...

We present a study of the acoustic source parameters describing glottal flow waveforms generated by the two-mass model for vocal fold oscillations. Numerical measurements of the acoustic parameters as a function of model parameters are presented. Conclusions are drawn from these results, concerning the correlations between acoustic parameters, the effect of the vocal tract, the different regime...

the laryngeal mask airway (lma) is an important addition to the anesthetist's equipments. however, its usage may involve some complications. we have encountered an unusual and potentially serious complication using this equipment. a 45-year old man underwent cataract surgery under general anesthesia. after the induction of anesthesia, a size 4 of the reusable classic lma was inserted without an...