نتایج جستجو برای: langendorff

تعداد نتایج: 1716  

Journal: :Advanced materials 2015
Lizhi Xu Sarah R Gutbrod Yinji Ma Artin Petrossians Yuhao Liu R Chad Webb Jonathan A Fan Zijian Yang Renxiao Xu John J Whalen James D Weiland Yonggang Huang Igor R Efimov John A Rogers

Advanced materials and fractal design concepts form the basis of a 3D conformal electronic platform with unique capabilities in cardiac electrotherapies. Fractal geometries, advanced electrode materials, and thin, elastomeric membranes yield a class of device capable of integration with the entire 3D surface of the heart, with unique operational capabilities in low power defibrillation. Co-inte...

2003
I Provaznik M Novakova M Blaha M Chmelar

Myocardial ischemia is the most common cause of death in the developed countries. The most severe manifestation is sudden death due to electrical instability, terminating in ventricular fibrillation or heart arrest. This study is based on experiments in which electrograms and monophasic action potentials are recorded from isolated guinea pig hearts perfused according to Langendorff during vario...

2012
Ya-Jian Cheng Di Lang Shelton D Caruthers Gregory Lanza Igor Efimov Junjie Chen Samuel A Wickline

Duchene Muscular Dystrophy (DMD) is a lethal disease caused by ubiquitous lack of dystrophin, but the interaction with regional cardiac mechanical forces that may facilitate eventual expression of abnormal contractile function is unknown. Diffusion tensor MRI (DTI) was used to evaluate function in Langendorff perfused hearts in the mdx mouse model of DMD. Abnormal calcium kinetics (by optical m...

2005
Ewa Karwatowska-Prokopczuk Ake Wennmalm

Endothelin is a 21-residue peptide formed during incubation of isolated porcine endothelial cells. Due to its pronounced vasoconstrictor activity, endothelin has been proposed to play a role in the regulation of vascular tone. We studied the effects of synthetic endothelin (0.1-10 nM) on coronary flow, mechanical performance, myocardial oxygen uptake, and formation of purines, and outflow of 6-...

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