نتایج جستجو برای: lactamases has been prevailed among bacteria
تعداد نتایج: 4193185 فیلتر نتایج به سال:
Background and purpose: : Klebsiella pneumoniae has emerged as a significant opportunistic pathogen responsible for nosocomial infections. This bacteria is frequently resistant to multiple classes of antibiotics such as family of beta-lactam antibiotics. β-lactamases enzyme represent the main mechanism of bacterial resistance to β-lactam antibiotics. This study was conducted to determi...
Carbapenem antibiotics have been used to counteract resistant strains of bacteria harboring -lactamases and extended-spectrum -lactamases. Four enzymes from the class A group of -lactamases, NMC-A, IMI-1, SME-1, and KPC-1, efficiently hydrolyze carbapenem antibiotics. Sequence comparisons and structural information indicate that cysteines at amino acid residues 69 and 238, which are conserved i...
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