The formation of the labyrinth layer is a critical step of placental development. The transcription factor glial cells missing 1 (Gcm1) plays a pivotal role in labyrinth development, but the sequence of events controlling its expression has not been identified yet. Our studies presented herein show that Gcm1 expression occurs in three distinct phases during placental development, each specific ...

PURPOSE This pilot study examines the effects of walking a labyrinth. METHOD A convenience sample of 25 community members participated in a four-group, repeated measures study to gather information about vital signs and affect before and after labyrinth walks. Because of the small sample size, results were inspected for effect size (ES) differences in pre-to postcomparisons. Mean postwalk sco...

In this paper, we consider the problem of navigating a robot with limited abilities concerning computing power, memory, and sensors through a labyrinth with one-way roads. Escaping from a labyrinth is a task which is widely explored. Many algorithms with different advantages and different areas of application are known. Usually, labyrinths are given as polygonal scenes or (directed) graphs. Whi...

We report the progressive otic capsule demineralization around the membranous labyrinth and facial nerve in an adult patient with osteogenesis imperfecta tarda. Whereas the initial CT scan showed bandlike, undermineralized pericochlear areas, 2 years later, repeat CT performed because of hearing deterioration showed progression of these findings to the promontory, the round window niche, and th...

A 6 week labyrinth walking program was pilot tested in a correctional setting and goals were to: 1) determine the feasibility of a labyrinth walking curriculum; 2) pilot test measures of health related quality of life (QOL) (pre and post-surveys) and blood pressure; and 3) examine the influence of relationship-centered teaching on subject satisfaction. Relational communication was used as a fra...

Starting with genetic or environmental perturbations, disease progression can involve a linear sequence of changes within individual cells. More often, however, a labyrinth of branching consequences emanates from the initial events. How can one repair an entity so fine and so complex that its organization and functions are only partially known? How, given the many redundancies of metabolic path...

In this paper, we introduce a new approach to computeraided microtonal improvisation by combining methods for (1) interactive scale navigation, (2) real-time manipulation of musical patterns and (3) dynamical timbre adaption in solidarity with the respective scales. On the basis of the theory of well-formed scales we offer a visualization of the underlying combinatorial ramifications in terms o...

The bony labyrinth of mammals, a delicate and complex cavity within the petrosal, houses the organs of hearing and equilibrium of the inner ear. Because this region is typically lodged deep within the skull, there have been few morphological studies of the bony labyrinth in fossils—where it frequently is completely enveloped by surrounding bone and sediment matrix. The recent development of hig...

Knowledge of the pathophysiology of vestibular disorders is essential for a logical accurate evaluation and management of the vertiginous patient. The diagnosis of vestibular system disease, particularly of peripheral disorders, depends primarily on a carefully obtained history with some assistance from tests of hearing function and vestibular sensitivity (caloric, positional tests). Radiologic...

The membranous labyrinth is contained within the bony labyrinth and surrounded by perilymph. The only two 'potentially yielding' parts of the otherwise solid bony labyrinth are the oval and round windows, which by their relative movements, pressure differentials and resilience are responsible for all the functions attributed to the inner ear. In pathologies, such as trauma, infection or occasio...