Three-dimensional calibration surfaces, along with downhole fractionation corrections, can provide improved accuracy for trace element concentration analysis by LA-ICP-MS.

The correlation between non-uniform gas flow patterns in large ablation cells and the resulting elemental fractionation is investigated compared to two-volume cells.

Hyaluronic acid drug conjugates can target anti-cancer drugs directly to tumor tissue for loco-regional treatment with enhanced bioavailability, local efficacy and reduced toxicity. In this study, the distribution and pharmacokinetics of hyaluronic acid carrier and a conjugated cisplatin anti-cancer drug were tracked by lanthanum (III) [La(III)] affinity tagging of the nanocarrier. The strong b...

Although a variety of techniques are available to measure nanoparticles, single particle ICP-MS (SP-ICP-MS) has become increasingly important due to its speed and ability to measure environmentally relevant low nanoparticle concentrations, surpassing the limitations of light-based technologies.6-7 Monitoring Cerium Dioxide and Zinc Oxide Nanoparticles through Drinking Water Treatments using Sin...

A new experiment using laser ablation with inductively coupled plasma mass spectrometry (LA-ICP-MS) was designed for chemistry undergraduate students. While most analytical methods only provide information on the amount of analyte, LA-ICP-MS allows extra distribution element in sample. Because it achieves excellent limits detection (sub μg·g–1) and high spatial resolution (micrometer scale), is...

Las indicaciones para intervención coronaria percutánea (ICP) siguen evolucionando debido al desarrollo continuo de la tecnología, a criterios de selección más amplios para pacientes y lesiones y a nuevas evidencias advenidas de ensayos clínicos. Los resultados principales del estudio COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation) generaron una controvers...

The technique of coupling liquid chromatography to inductively plasma mass spectrometry (ICP-MS) is reviewed. A brief introduction to the ICP-MS instrument is given as well as methods to couple the two analytical instruments together. The various types of LC that have been used with ICP-MS detection are discussed and advantages over traditional methods of detection are highlighted, such as the ...

Magmatic sulfide deposits are the most significant source of platinum-group elements (PGE) in the world. Key to understanding their genesis is determining the processes and timing of sulfide saturation, metal enrichment and crustal contamination. In this study, we have identified droplets of magmatic sulfide from the Platreef, South Africa, where droplets of sulfide have been trapped in the ear...