Results In the study period 3,929 patients with AD (with 353 positive cases) presented to the Infectious Diseases Hospital out of which 2,550 children (with 301 positive cases) and 1,371 adults (with 52 positive cases). In children rotavirus enteritis ranked first in the etiology of infectious enteritis with a confirmed etiology of 62% over the entire period (186 cases) with a peak incidence in...

Enterobacteria, in particular Klebsiella spp., have been implicated in the aetiopathogenesis of ankylosing spondylitis. A comprehensive examination of the faecal flora of 82 patients with ankylosing spondylitis, either primary (67), or in association with inflammatory bowel disease (4), reactive arthritis (6) or psoriatic arthritis (5), was performed and compared with that of a control populati...

Bacterial names are continually being changed in order to more adequately describe natural groups (the units of microbial diversity) and their relationships. The problems in Klebsiella taxonomy are illustrative and common to other bacterial genera. Like other bacteria, Klebsiella spp. were isolated long ago, when methods to identify and classify bacteria were limited. However, recently develope...

Multiplex-PCR assay for identification of Klebsiella pneumoniae isolates carrying gene clusters for biosynthesis of capsular polysaccharide (CPS) types K1 and K2 was developed. Genes wzc and orf10 of the cps cluster were applied as K1 and K2 specific markers respectively. The assay specificity was confirmed using 147 isolates of Klebsiella spp. including 77 K-antigen reference strains. The mult...

The capsular polysaccharide (CPS) plays important role in Klebsiella spp pathogenesis. Capsular types K1 and K2 of Klebsiella pneumoniae are considered most virulent for humans. The capsule biosynthesis region flanking genes galF and gnd from clinical isolates and reference strains of K. pneumoniae were screened for polymorphism. Nucleotide sequence analysis of galF and gnd revealed a high hete...

The study was carried out to investigate the current antibiogram status of bovine mastitis in and around Ranchi. The prevalence of mastitis was assessed by the results of bacteriological evacuation of mastitic milk samples collected from mastitis cases. A total of 150 cases of mastitis were studied for isolation followed by antibiotic sensitivity test. The major prevalent pathogens isolated wer...

To investigate the occurrence of different Klebsiella spp. in aquatic environments, a total of 208 samples of natural surface waters was examined. From half (53%) of these samples, 123 Klebsiella strains were isolated, the most common species being Klebsiella pneumoniae. A comparison of these isolates to a group of 207 clinical K. pneumoniae isolates demonstrated that water isolates of K. pneum...

Background: Community-acquired infections by multidrug-resistant (MDR), extended-spectrum β-lactamase (ESBL) producing Klebsiella species (Klebsiella spp.) is of major concern worldwide. Antibiotic resistance, production of extended-spectrum β-lactamases (ESBLs), and carbapenemases, as well as the presence of classes 1, 2, and 3 integrons in outpatient isolates of Klebsiella collected from Yazd...

Klebsiella species normally produce a chromosomally encoded group 2b, or molecular class A, -lactamase. In most strains of Klebsiella pneumoniae the enzyme has an isoelectric point (pI) of 7.6, identical to that of the plasmidencoded -lactamases SHV-1 and SHV-2, and is assumed to be SHV-1. This -lactamase is transposon-encoded and it has been postulated that it might have arisen as a klebsiella...

BACKGROUND & OBJECTIVE Clinical laboratories need to develop quick screening methods for detection of extended spectrum beta-lactamase (ESBL) producing strains, so that the appropriate medication can be started without delay. In this study, we report the screening sensitivity of four representative antimicrobial agents i.e., cefpodoxime, cefotaxime, ceftazidime and aztreonam, commonly used for ...