Nephroblastoma (Wilms tumor – WT) is the most common kidney among pediatric population, fifth malignant neoplasms and third solid tumors. The type of WT sporadic unilateral. occurs either as an isolated, nonsyndromic or syndromic one belonging to spectrum a variety genetic syndromes. Molecular testing should be considered in include multigene panel whole exome sequencing (WES); cases single-gen...

INTRODUCTION Renal oncocytomas are benign neoplasms derived from cells of the distal renal tubule, and comprise 5% to 7% of primary renal neoplasms. Oncocytomas are mostly asymptomatic, and the majority of tumors are discovered incidentally. In this case report, we present a case of a patient with a giant oncocytoma arising from her left kidney. CASE PRESENTATION We describe a 25-year-old Tur...

conclusions pnet/ews should be included in the differential diagnosis of renal tumors in symptomatic young adults. patients with localised pnet/ews treated with a combination of surgery and chemotherapy have an excellent chance of long-term survival, as in the case we have presented. introduction primitive neuroectodermal tumor (pnet)/ewing’s sarcoma (ews) belongs to a family of neoplasms that ...

Background & objective:Primary pleural neoplasms are rare entities compared with the pleural involvement by metastatic carcinoma. The current study aimed at investigating the complete spectrum of pleural neoplasms and differentiating between them with the aid of immunohistochemistry (IHC). Methods: Consecutive pleu...

Reported herein are simultaneous double primary clear cell carcinomas arising from liver and kidney. A 63-year-old man underwent a partial wedge nephrectomy of the right kidney in a surgical resection for hepatocellular carcinoma. Coincidently, on histology the tumors in liver and kidney were consisted of clear cancer cells, which arranged in haphazardly intermixed pattern without capsules. Imm...

synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...

Glomerular sparing (GS) is defined as a unique growth pattern in which tumor cells replace the majority of renal tubes and overrun intact glomeruli. This phenomenon has been well recognized by pathologists as a typical infiltrative pattern and some studies suggested it was an independent risk factor. Here, we study the clinical, pathological, and immunohistochemical features of primary kidney n...

Surgically removed solid human benign and malignant neoplasms and nonneoplastic tissues were examined for the presence of transforming growth factors (TGFs). TGFs are polypeptide growth factor-like substances which cause the appearance of a reversible neoplastic phenotype in nontransformed, anchorage-dependent cells in culture, including the induction of the ability to grow while suspended in s...

Objective: to evaluate trends of survival in nine index malignant neoplasms (iMNs), which are screened at the first stage Dispanserization certain groups adult population (DCGAP), on data Arkhangelsk regional cancer registry over a period 2006-2019.
 Materials and methods. We compared two seven-year periods 2006-2012 2013-2019, before after introduction DCGAP. The 1- 5-year cancer-specific...