abstract background and objective: according to the issue of dependence and tolerance in addicted patients, the inefficiency of existing treatments and the new recommendation for drug combination therapy for diseases in modern pharmacology, the present study examined the effect of methadone and valproate combination on morphine dependence and tolerance. materials and methods: ninety-eight male ...

introduction: ghrelin is a potent orexigenic agent in rodents and humans. some studies have shown that ghrelin participates in the adaptive response to weight loss and plasma concentration of ghrelin rises with dieting. on the other hand, weight loss and fasting is accompanied by increased levels of epinephrine and cortisol. in this study, we investigated the effects of epinephrine and cortisol...

introduction: we have recently reported the presence of two potassium currents with 598 and 368 ps conductance in the rough endoplasmic reticulum (rer) membrane. the 598 ps channel was voltage dependent and atp sensitive. however, the 368 ps channel was rarely observed and its identity remained obscure. since cationic channels in intracellular organelles such as mitochondria and rer play import...

introduction: microleakage can result in failure of endodontic treatment. an important characteristic of endodontic sealer is sealing ability. the aim of this experimental study was to compare the apical leakage of teeth obturated with gutta-percha and three different sealers (resin- and zinc oxide eugenol-based) with/without smear layer (sl). materials and methods: in this study, 100 single-ro...

objective: the aim of this study is to measure the effect of different condensation pressure on the microleakage of mineral trioxide aggregate (mta).  methods: this study was an invitro study. a total of 55 single rooted straight-canal human extracted sound teeth free of cracks or calcification were selected. teeth were sectioned from cej region at 3 mm above the root apex. remaining specimens ...

background: more psychiatric visits, especially non-emergency ones, to emergency departments (eds) of general hospitals have been observed in recent years. the aim of this study was to determine the characteristics of psychiatric visits to the ed of rasoul-e-akram hospital, tehran, iran. methods: in this cross-sectional study, during a two-month period, all psychiatric presentations and consult...

abstract background & aim: food insecurity is defined as limited availability at all times to sufficient food of an active life. the aim of this study was assessing the food insecurity status and some associated socioeconomic factors in women with metabolic syndrome. methods: the present cross-sectional study was conducted on 130 women between 30-60 years of age with metabolic syndrome referred...

objective: the aim of the present study was to investigate the prevalence of hypertension and type ii diabetes in elderly iranianresidents of the kahrizak charity foundation(kcf). materials and methods: in this cross-sectional study, a total of two hundred sixty eight men and women ≥60 years were studied. the data were collected during annual health examination of the elderly residents in kcf. ...

background : there are a few studies to assess nurses’ sleep quality and sleepiness in the iranian context. this study thus was carried out to examine the prevalence of sleepiness and sleep quality among nurses in south east of iran.   subjects and methods : the study applied a descriptive, explorative design.252 nurses randomly selected from kerman university hospitals during winter 2009. usin...

background and objective: gastroenteritis is one of the most important diseases in the world. this disease is more critical among children, people with immune deficiency and the sufferers from mal-nutrition. shigella spp. as the most important cause of dysentery, causes much mortality around the world. increasing antibiotic resistance is one of the major health problems. this research aimed to ...