Wilson's disease (WD) is a rare hereditary caused by deficiency of the ATF7B transporter. The accumulation copper can cause damage to organs and cells, mainly liver. Copper exposure modulate cytokine synthesis through molecular cellular signaling pathways, including nuclear transcription factor NF-kB pathway. main regulator inflammation cell death, acts as central link between liver damage, fib...

This study aims to determine what factors influence the selection of MKJP (Long Term Contraception Method) through mobile family planning program in Prabumulih City. research method is a quantitative analysis using secondary data from 2021 Family Data Collection (PK21). The results showed that Nagelkerke R Square value was 0.117 and Cox & Snell 0.010, indicating independent variable's abili...

The purpose of this research is to analyze the phenomenon Unmet need in KB village. This method a quantitative analysis using secondary data from 2021 Family Data Collection (PK 21). population used was all PUS Rambang Kapak Tengah District with sample 326 PUS. Descriptive statistical study through three stages, namely: univariate analysis, bivariate (Chi Square) and multivariate. results are f...

A 4.2-kilobase (kb) cryptic plasmid is present in 96% of isolates of Neisseria gonorrhoeae. An inability to construct isogenic derivatives which vary in the presence of the 4.2-kb plasmid has prevented the study of its function. We report a method to deliver an intact 4.2-kb plasmid into plasmidless gonococcal strains. The method involved transformation with novel 15.7-kb hybrid penicillinase-p...