Adamantiades-Behçet's disease (ABD) is a multisystemic vasculitic disease. It is most prevalent in the Eastern Mediterranean countries and the Eastern region of Asia. Its effect on the eye can range from mild to debilitating, resulting in total blindness. A necrotizing and obliterative vasculitis affects both arteries and veins of organs. Recurrent attacks of uveitis, oral aphthous ulcers, skin...

BACKGROUND Patients with acquired brain damage (ABD) have suffered a brain lesion that interrupts vital development in the physical, psychological and social spheres. Stroke and traumatic brain injury (TBI) are the two main causes. The objectives of this study were to estimate the incidence and prevalence of ABD in the population of the Basque Country and Navarre in 2008, to calculate the assoc...

the A8, and it has been shown that the gene double sex (dsx) represses growth in the former, probably by repressing decapentaplegic (dpp) expression. We show here that the absence of Abd-B or homothorax (hth) in this segment also increases growth and activates the expression of dMyc and dpp. The effects on the size of the A9 can be rescued if dpp activity is reduced. Neither Abd-B, dsx, nor hth...

the A8, and it has been shown that the gene double sex (dsx) represses growth in the former, probably by repressing decapentaplegic (dpp) expression. We show here that the absence of Abd-B or homothorax (hth) in this segment also increases growth and activates the expression of dMyc and dpp. The effects on the size of the A9 can be rescued if dpp activity is reduced. Neither Abd-B, dsx, nor hth...

A radiolabeled anti-HER2 Affibody molecule (Z(HER2:342)) targets HER2-expressing xenografts with high selectivity and gives good imaging contrast. However, the small size (approximately 7 kDa) results in rapid glomerular filtration and high renal accumulation of radiometals, thus excluding targeted therapy. Here, we report that reversible binding to albumin efficiently reduces the renal excreti...

Hox transcription factors specify distinct cell types along the anterior-posterior axis of metazoans by regulating target genes that modulate signaling pathways. A well-established example is the induction of Epidermal Growth Factor (EGF) signaling by an Abdominal-A (Abd-A) Hox complex during the specification of Drosophila hepatocyte-like cells (oenocytes). Previous studies revealed that Abd-A...

This paper considers the communication and storage costs of emulating atomic (linearizable) read/write shared memory in distributed messagepassing systems. We analyze the costs of previously-proposed algorithms by Attiya, Bar-Noy, and Dolev (the ABD algorithm) and by Fan and Lynch (the LDR algorithm), and develop new coding-based algorithms that significantly reduce these costs. The paper conta...

There are many examples within gene complexes of transcriptional enhancers interacting with only a subset of target promoters. A number of molecular mechanisms including promoter competition, insulators and chromatin looping are thought to play a role in regulating these interactions. At the Drosophila bithorax complex (BX-C), the IAB5 enhancer specifically drives gene expression only from the ...

The past few years have witnessed smartphones going from closed platforms containing only pre-installed applications to open platforms hosting a variety of thirdparty applications. Unfortunately, this change has also led to a rapid increase in Abnormal Battery Drain (ABD) problems caused by software defects, misconfiguration, or environmental changes. Such issues can drain a fullycharged batter...