By introducing probabilistic modeling approaches, the interface transition zone (ITZ) and bulk paste (BP) of concrete are investigated on basis nanoindentation results, especially with respect to relationship between microstructure mechanical properties cementitious materials. The investigation probability density function (PDF) random field for revealed that same ITZ BP usually yield PDF, whic...

Abstract The mechanical degradation of concrete structures is a phenomenon dependent on the material heterogeneity observed at mesoscale. As localized phenomenon, structural members and may be simulated using concurrent multiscale analysis technique. Thus, only most critical regions are modeled in mesoscale, reducing computational cost compared to simulation entire structure this scale. This wo...

The paper presents results of tests on the effect addition fly ash (FA) in amounts 0%, 20%, and 30% by weight cement interfacial microcracks concrete composites subjected to dynamic loads. analyses were carried out based microstructural using a scanning electron microscope (SEM). average width (Wc) transition zone (ITZ) coarse aggregate with matrix was evaluated. During studies beneficial FA re...

Concrete is a multi-phase heterogeneous material in which the interfacial transition zone (ITZ) between aggregates and mortar significantly affects cracking behaviour of concrete, especially under tensile load. In this paper, artificial neural network (ANN) method applied predicting fracture properties ITZ concrete. To form data pool for training ANN, large number two-dimensional (2D) meso-scal...

Isavuconazole (ISZ) is a newly available broad-spectrum triazole agent recently approved for the treatment of both invasive aspergillosis and mucormycosis. The aim of this study was to develop a simple and reliable method for therapeutic drug monitoring (TDM) of ISZ in human plasma samples. The method involves using a kit from ChromSystems intended for TDM of itraconazole (ITZ), posaconazole (P...

Moisture flow in porous media is the driving force behind early age drying shrinkage. Fracture in the interfacial transition zone (ITZ), between cement paste and aggregateinclusion, is related to restraint caused by, among others, aggregates that obstruct free deformation of the paste. Environmental Scanning Electron Microscope (ESEM) test results are used as a base for the developed method for...