A total of forty-three isolates of Ascochyta rabiei obtained from infected seeds and plants of chickpea from different areas of Kermanshah, Lorestan, Hamadan, Kordestan, and East and West Azarbaijan provinces were studied during the period 1996-1999. A rapid and simple method was developed for pathogenicity test in CDA (chickpea seed meal dextrose agar) medium. CDA medium was inoculated with di...

Screening bacteria for bioactive compounds is the first step in the drug discovery programs. The aim of the present research was to achieve cytotoxic and antioxidant metabolites from actinobacteria of Persian Gulf sediments and to investigate the effects of combinations of seven treatments and six isolation media on the selective isolation process. A total of 395 actinobacterial isolates were c...

Background: Pseudomonas aeruginosa is an important opportunistic pathogen causes clinical infections among burn patients. Metallo-β-lactamases (MBLs) are important mechanisms of Carbapenem (drug of choice) resistance among Pseudomonas aeruginosa isolates. The aims of this study were to determine the antibiotic susceptibility pattern and to detect the prevalence of MBLs among Pseudomonas aer...

Background: Clindamycin is a suitable antibiotic for treatment of skin and soft tissue infections. Moreover, it can suppress toxin production in many pathogenic bacteria such as S. aureus. There are two mechanisms of resistance in this antibiotic. Constitutive resistance can be detected by standard disk diffusion method but in the case of inducible resistance, D-test should be carried out. The ...

Abstract       Background and objectives: More Candida albicans strains are reported resistant to fluconazole in patients with AIDS, cancer and organ recipients. Fluconazole resistance can be attributed to changes in pathways of sterol biosynthesis, mutation in or overexpression of ERG11 and the expression of CDR1, CDR2, and MDR1. This study aimed to compare the ex...