The authors focus iron intake regulation in the body and the probable mechanisms related to iron absorption. They analyze the impact of iron absorption deficiency resulting in iron deficiency anemia, a public health issue of great impact in the world influencing child and maternal health risk increase. This paper aims at highlighting the problems affecting the uptake or inhibiting processes of ...

Nutritional iron-deficiency anaemia (IDA) is the most common disorder in the world, affecting more than two billion people. The World Health Organization's global database on anaemia has estimated a prevalence of 14% based on a regression-based analysis. Recent data show that the prevalence of IDA in pregnant women in industrialized countries is 17.4% while the incidence of IDA in developing co...

Neisseria meningitidis requires iron, and in the absence of iron alters its gene expression to increase iron acquisition and to make the best use of the iron it has. During different stages of colonization and infection available iron sources differ, particularly the host iron-binding proteins haemoglobin, transferrin, and lactoferrin. This study compared the transcriptional responses of N. men...

The longitudinal and lateral shower profiles for 500 MeV electrons in iron are studied using dosimetry and activation techniques. The results are compared with Monte Carlo simulations and other previously published data. The agreement between the data and the EGS4 simulation results is good; a simple shower profile parametrization of type kz exp (−βz) does not represent the experimental data we...

Isobaric and cooling zone of iron ore reactor have been simulated. In this paper, heat and mass transfer equation are formulated to perform the temperature and concentration of gas and solid phase respectively. Temperature profile for isobaric zone is simulated on the range temperature of 873-1163K while cooling zone is simulated on the range temperature of 733-1139K. The simulation results hav...

Background. Administration of ferric pyrophosphate citrate (FPC, TrifericTM) via hemodialysate may allow replacement of ongoing uremic and hemodialysis-related iron losses. FPC donates iron directly to transferrin, bypassing the reticuloendothelial system and avoiding iron sequestration. Methods.Two identical Phase 3, randomized, placebo-controlled trials (CRUISE 1 and 2) were conducted in 599 ...

BACKGROUND Current guidelines are inconclusive regarding intravenous (IV) iron for treatment of chemotherapy-induced anaemia (CIA). MATERIAL AND METHODS Systematic review and meta-analysis of randomised controlled trials comparing IV iron with no iron or oral iron for treatment of chemotherapy induced anaemia (CIA). PRIMARY OUTCOMES haematopoietic response and red blood cell (RBC) transfusi...

We compile the multi-band spectral energy distribution (SED) of Seyfert 1 galaxy NGC4593, and investigate its optical-to-ultraviolet (OUV) continuum and iron Kα line profile. No strong “big blue bump” is found in OUV band. The iron Kα line profile is not as broad as expected from a disk which extends down to the last stable orbit. Both of them can be modeled by a truncated thin disk, and suppor...

Background Intravenous iron allows for efficient and well-tolerated treatment in iron deficiency and is routinely used in diseases of the gastrointestinal tract. Objective The aims of this study were to determine the probability of relapse of iron deficiency over time and to investigate treatment routine, effectiveness, and safety of iron isomaltoside. Methods A total of 282 patients treate...

The pathophysiology of akathisia still remains controversial. Iron deficiency was proposed to be an important factor in the development of akathisia. In the present study, it was aimed to compare levels of serum iron and linked variables in chronic akathisic (n=30), and non-akathisic patients (n=30) with schizophrenia and healthy controls (n=30) because of the controversy in the association of ...