نتایج جستجو برای: iron oxide nanoparticles
تعداد نتایج: 396735 فیلتر نتایج به سال:
several mri contrast agents (cas) are used in medical diagnosis that gadolinium (gd3+) is the most widely used as contrast agents. unfortunately, its toxicity is due to its inefficiency. in this review, we discuss about the ability of spions in mri and application in multiple sclerosis diagnosis. superparamagnetic iron oxide nanoparticles (spions) such as magnetite nanoparticles are used as goo...
Using magnetic nanoparticles to absorb alternating magnetic field energy as a method of generating localized hyperthermia has been shown to be a potential cancer treatment. This report demonstrates a system that uses tumor homing cells to actively carry iron/iron oxide nanoparticles into tumor tissue for alternating magnetic field treatment. Paramagnetic iron/ iron oxide nanoparticles were synt...
Iron oxide nanoparticles with engineered physical and biochemical properties are finding a rapidly increasing number of biomedical applications. However, a wide variety of safety concerns, especially those related to oral exposure, still need to be addressed for iron oxide nanoparticles in order to reach clinical practice. Here, we report on the effects of chronic oral exposure to low doses of ...
Targeting neuropeptide systems is important for future advancements in treatment of neurological and psychiatric illnesses. However, many of the peptides and their analogs do not cross the blood-brain barrier (BBB) efficiently. Nanoparticles such as iron oxide can cross the BBB, and here we describe a novel method for the conjugation of a peptide antisauvagine-30 (ASV-30) to iron oxide nanopart...
AIMS To evaluate the feasibility of loading resting monocytes/macrophages by intravenous (i.v.) injection of fluorescent iron oxide nanoparticles prior to injury and tracking of these cells in the very same animal to myocardial infarction (MI) by magnetic resonance imaging (MRI) and optical imaging. METHODS AND RESULTS Rats were injected with fluorescent iron oxide nanoparticles (10 mg/kg) (n...
The relaxation rates of iron-oxide nanoparticles compartmentalized within cells were studied and found to satisfy predictions of the static dephasing (SD) regime theory. THP-1 cells in cell culture were loaded using two different iron-oxide nanoparticles (superparamagnetic iron-oxide (SPIO) and ultrasmall SPIO (USPIO)) with four different iron concentrations (0.05, 0.1, 0.2, and 0.3 mg/ml) and ...
The stability of enzyme-conjugated magnetic iron oxide nanoparticles in plasma is of great importance for in vivo delivery of the conjugated enzyme. In this study, β-glucosidase was conjugated on aminated magnetic iron oxide nanoparticles using the glutaraldehyde method (β-Glu-MNP), and further PEGylated via N-hydroxysuccinimide chemistry. The PEG-modified, β-glucosidase-immobilized magnetic ir...
Background and purpose: The use of nanotechnology is increasing in different fields of medical sciences including diagnosis and treatment. Metal nanoparticles such as Iron nanoparticles are proposed as novel radiation-sensitizing agents in enhancing the efficiency of radiotherapy because they have a large number of atoms. This study aimed at investigating the radiosensitivity effect of dextran-...
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Background and Aim: Iron oxide nanoparticles are used in fields related to nanotechnology including ecology, magnetic storage, imaging and medicinal purposes. Iron nanoparticles produce reactive oxygen species (Ros). These materials are able to cross the placenta. The aim of this study was to investigate toxic effect of iron oxide nanoparticles on fetal lung in mice. <br ...
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