The myocardium, all parts of the conduction system, and the S-A node contained iron in six patients with acquired iron-storage disease. The nerve fibers and ganglia contained negligible amounts. No correlation was demonstrated between the amount of histochemically demonstrated iron in the myocardium and conduction system, or the amount of transfused iron, or the amount of quantitatively analyze...

Iron deficiency (ID) in early life is known to alter neurological development and functioning, but data regarding specific effects on dopamine biology are lacking. The objective of this study was to determine the extent of functional alterations in dopamine receptors in two dopaminergic tracts in young, growing, iron-deficient rats. Forty male and 40 female weanling Sprague-Dawley rats were fed...

BACKGROUND Adolescents, influenced by modern youth culture, may have a diet containing too little iron and other vital nutrients. MATERIALS AND METHODS Adolescents from Finnmark county, situated well above the arctic circle in Norway, from a Sami culture, and from a coastal culture, were examined to study hemoglobin, iron stores, dietary composition, food habits and life-style. A short interv...

The transferrin receptor, present on reticulocytes and nucleated cells in tissue culture, has been measured with both immunoassay techniques and transferrin binding studies. The total cellular immunoreactive receptor is rapidly lost from erythrocytes during the process of reticulocyte maturation (from as many as 400,000 molecules to <20,000 molecules/reticulocyte). This event parallels the loss...

Inspired by the active site structure of monoiron hydrogenase, a series of iron complexes are built using experimentally ready-made acylmethylpyridinol and aliphatic PNP pincer ligands. Density functional theory calculations indicate that the newly designed iron complexes are very promising to catalyze the formation of formic acid from H2 and CO2.

McAndrew et al. (1) report the crystal structure of NOV1, a stilbene-cleaving carotenoid cleavage oxygenase (CCO), in substrate-free and substrate/productbound forms, all of which with dioxygen (O2) bound to the nonheme iron center of the enzyme. In mononuclear nonheme iron enzymes studied to date, the Fe–O2 interaction is strongly promoted by the binding of organic substrate/cofactor at or nea...

Nanoporous iron metal foams were synthesized by an improved sol-gel autocombustion method in this report. It has been confirmed to be pure phase iron by X-ray diffraction measurements. The nanoporous characteristics were illustrated through scanning electron microscope and transmission electron microscope images. Very low density and quite large saturation magnetization has been performed in th...

Detailed knowledge of the phase diagram and the nature of the competing magnetic and superconducting phases is imperative for a deeper understanding of the physics of iron-based superconductivity. Magnetism in the iron-based superconductors is usually a stripe-type spin-density-wave, which breaks the tetragonal symmetry of the lattice, and is known to compete strongly with superconductivity. Re...

Using density functional calculations, it is shown that pure MnN is stable in zincblende rather than in the experimentally reported distorted rocksalt structure. However, about 4% N vacancies are found to stabilize the rocksalt structure. It is found that C and O substitutions on N and Ga on Mn also favor rocksalt but Ni, SN, FeMn, and CoMn stabilize zincblende. This suggests that zincblende Mn...

We have carried out first-principles all-electron calculations of the (001)-projected 2D electron momentum density and the directional Compton profiles along the [100], [001] and [110] directions in the Fe-based superconductor LaOFeAs within the framework of the local density approximation. We identify Fermi surface features in the 2D electron momentum density and the directional Compton profil...