Free erythrocyte porphyrin:hemoglobin (FEP:Hb) ratios were determined on 20 infants with iron-deficiency anemia. FEB:Hb ratios were compared with simultaneously drawn serum ferritin and serum transferrin saturation levels. FEP:Hb ratios dropped steadily during treatment of the anemic infants, but remained elevated compared to age-matched nonanemic infants, until the anemia was corrected. FEP:Hb...

We evaluated the use of transferrin receptor (TfR) in serum as an index of iron deficiency in 19 patients diagnosed as having iron-deficiency anemia, in 17 patients with anemia of chronic disease, and in a control group of 19 nonanemic patients who underwent elective ocular or nasopharyngeal surgery. The assessment of iron status of the anemic patients was based on the presence of stainable iro...

Aim: The prevalence of celiac disease (CD) in patients with iron deficiency (ID) is estimated at 0-6% in European countries. The prevalence of celiac disease in patients with iron deficiency in the USA is unknown. Given the treatable nature of gluten hypersensitivity, estimating the prevalence of CD in patients with ID can help to determine the need to screen these patients for occult CD. Metho...

background: the aim of the present study was to assess the mean corpuscular volume (mcv) as a surrogate marker for detecting early iron deficiency prior to definitive investigation and treatment. materials and methods: this study was done on one hundred students in swada preparatory school – sharkia governorate from 2010 to 2011. they were subdivided into three groups: group (a): comprised of 3...

background: iron deficiency anemia (ida) is the most common micronutrient deficiency in the world and almost a third of the world's population is involved with ida. it even in mild type, could lead to serious disorders such as impairment of learning and mental focus. reduction of iron resources results in an imbalance in the physiological function. with regard to the role of iron in myelin...

L and La Rosa (1) investigated the occurrence of celiac disease in patients with hepatitis B by screening their sera with anti-endomysial and anti-tissue transglutaminase antibodies—both of which are sensitive serological tests for celiac disease. The authors found no one with celiac disease in 60 patients who had contracted hepatitis B infection in childhood. As they admitted, the power of the...

Anemia in inflammatory bowel disease (IBD) is a prototype of a combination of iron deficiency and anemia of inflammation (i.e. anemia of chronic disease; ACD) which is caused by negative effects of an activated immune system at different levels of erythropoiesis. Besides iron deficiency and ACD, metabolic disturbances and vitamin deficiencies as well as commonly used IBD drugs can aggravate ane...

Inflammation can lead to malabsorption of important micronutrients such as iron. Malabsorption and nutritional deficiency can be caused by a variety of pathological and environmental factors causing a range of other symptoms commonly caused by both H. pylori infection and coeliac disease (CD). National guidelines suggest the routine taking of duodenal biopsies to exclude CD when investigating p...

The most usual causes of iron deficiency anemia are related to the digestive disease: acute or chronic blood loss (due to cancer or polyp of colon or stomach, peptic ulcer, nonsteroidal anti-inflammatory drugs use, inflammatory bowel disease, vascular lesions) or reduced iron absorption (in celiac disease, small bowel bacterial overgrowth, Whipple’s disease, lymphangiectasia, gastrectomy and ga...