Epidemiology In the developed world, 2-5% of adult men and postmenopausal women have IDA. [4] Iron deficiency and IDA are common in young children. [5] Iron deficiency is the most common cause of anaemia in pregnancy worldwide; severe anaemia can have very serious consequences for mothers and babies. [6] Premenopausal women have a higher incidence of IDA because of heavy menstrual blood losses ...

The utilization of iron dextran was investigated in normal subjects, in patients with iron-deficiency anaemia, and in anaemias associated with rheumatoid arthritis, reticulosis, and uraemia. Utilization of iron for haemoglobin formation at 14 days was found to be depressed in patients with rheumatoid arthritis, reticulosis, and uraemia, but when a concomitant iron-deficiency anaemia was present...

Background: Iron deficiency (ID) is the most frequent cause of anaemia (IDA) in women of reproductive age and pregnant women. Recommended cut-off value for anaemia in women of reproductive age is haemoglobin (Hb) <12.0 g/dL and in pregnancy Hb <11.0 g/dL. Serum ferritin <15-20 μg/L is consistent with ID; Hb below cut-off values and ferritin <12-15 μg/L is consistent with IDA. Methods: Literatur...

OBJECTIVES To describe a case of Meckel's diverticulum with an unusual complication of iron deficiency anaemia due to chronic intestinal bleeding. CLINICAL PRESENTATION AND INTERVENTION A 12-year-old boy presented with bloody diarrhoea and abdominal pain in association with a long-standing history of black stools and progressive pallor. Biochemical tests revealed low serum iron (1.2 mmol/l) i...

This report demonstrates pulmonary haemorrhage as a differential cause of anaemia. Idiopathic pulmonary hemosiderosis is a rare disease in children; it is classically described as a triad of haemoptysis, pulmonary infiltrates on chest radiograph, and iron-deficiency anaemia. However, anaemia may be the only presenting feature of idiopathic pulmonary hemosiderosis in children due to occult pulmo...

MAIN DISORDERS OF IRON METABOLISM: Increased iron requirements, limited external supply, and increased blood loss may lead to iron deficiency (ID) and iron deficiency anaemia. In chronic inflammation, the excess of hepcidin decreases iron absorption and prevents iron recycling, resulting in hypoferraemia and iron restricted erythropoiesis, despite normal iron stores (functional iron deficiency)...

Strategies such as dietary diversification and food fortification have yielded significant results in controlling iron deficiency anaemia in developed countries. Reducing the prevalence of iron deficiency anaemia in developing countries is still a matter of importance. The major factors responsible for iron deficiency anaemia in the vulnerable segments of developing countries are reduced intake...

The aim of this review was to understand the landscape of serum ferritin in diagnosing iron deficiency in the aetiology of anaemia in pregnancy. Iron deficiency in pregnancy is a major public health problem leading to the development of anaemia. Reducing the global prevalence of anaemia in women of reproductive age is a 2025 global nutrition target. Bone marrow aspiration is the gold standard t...

Although the aetiology and pathological significance of chronic atrophic gastritis is still unknown, the incidence of the disorder in normal subjects and in a variety of pathological conditions is becoming known. Coghill (1960), in a full review of the subject, discussed the possible relationship between gastritis and hypochromic anaemia. It has been suggested that the gastric mucosal lesion ma...

BACKGROUND Iron supplementation is employed to treat post-malarial anaemia in environments where iron deficiency is common. Malaria induces an intense inflammatory reaction that stalls reticulo-endothelial macrophagal iron recycling from haemolysed red blood cells and inhibits oral iron absorption, but the magnitude and duration of these effects are unclear. METHODOLOGY/PRINCIPAL FINDINGS We ...