The identification of disease-associated genes has recently gathered much attention for uncovering disease complex mechanisms that could lead to new insights into the treatment of diseases. For exploring disease-susceptible genes, not only experimental approaches such as genome-wide association studies (GWAS) have been used, but also computational methods. Since experimental approaches are both...

BACKGROUND In response to high burden of opioid abuse in Iran, Ministry of Health has launched a large-scale opioid maintenance treatment program, delivered through a network of certified drug treatment centers. To promote opioid pharmacotherapies, there is an urgent need to develop and introduce evidence-based psychosocial interventions into the network. PATIENTS AND METHODS This is a random...

[1] Abstract: We conduct a comprehensive and quantitative analysis of similarities and differences between recent seismic tomography models of the Earth’s mantle in an attempt to determine a benchmark for geodynamic interpretation. After a spherical harmonic expansion, we find the spectral power and radial correlation of each tomographic model as a function of depth and harmonic degree. We then...

[1] Seismic tomography reveals two large, low-shear velocity provinces (LLSVPs) beneath Africa and the Pacific Ocean. These structures may have existed for several 100 Myr and are likely compositionally distinct based on observed seismic characteristics interpreted in light of geodynamic models and mineral physics constraints. We investigate the dynamics of the LLSVPs through the use of evoluti...

This paper introduces the concept of a dynamic key infrastructure for Grid. It utilises the properties of Identity-based Cryptography (IBC) to simplify key management techniques used in current Public Key Infrastructure (PKI) settings for Grid. This approach can offer greater simplicity, flexibility, and enhanced computation trade-offs.