نتایج جستجو برای: ionizing

تعداد نتایج: 14812  

Journal: :Radiation research 2007
Christie Vermeulen Barbara Bertocci Adrian C Begg Conchita Vens

Ionizing radiation induces a diverse spectrum of DNA lesions, including strand breaks and oxidized bases. In mammalian cells, ionizing radiation-induced lesions are targets of non-homologous end joining, homologous recombination, and base excision repair. In vitro assays show a potential involvement of DNA polymerase lambda in non-homologous end joining and base excision repair. In this study, ...

2016
Ya-Na Li Wen-Bo Zhang Jin-Hua Zhang Ping Xu Ming-Hua Hao

Ionizing radiation has the potential to cause extensive damage to living organisms. It can directly act on DNA, proteins and lipids, resulting in ionizing excitation and chemical bond cleavage, which can lead to molecular and cellular damage. Ionizing radiation can hydrolyze water molecules in the body, resulting in increased numbers of free radicals with strong oxidation ability. This process ...

Journal: :Brazilian dental journal 2008
George Boraks Flávio Silva Tampelini Kleber Fernando Pereira Renato Paulo Chopard

A common side effect of radiotherapy used in the treatment of oral cancer is the occurrence of structural and physiological alterations of the salivary glands due to exposure to ionizing radiation, as demonstrated by conditions such as decreased salivary flow. The present study evaluated ultrastructural alterations in the parotid glands of rats receiving a fractionated dose (1,500-cGy) of radia...

1998
Philip R. Maloney

We review the possible sources of ionizing photons within the Local Group. Throughout most of the LG volume, the cosmic background radiation will dominate, but locally (e.g., within d ∼ 100 kpc of the Galactic disk) stellar ionizing photons escaping from galaxies may dominate. The magnitude of the cosmic ionizing background should be determined in the very near future by observations of Hα emis...

2013
Jin Xiaoming Lin Dongsheng Yang Shanchao

The pulsed ionizing radiation effect of monolithic operational amplifiers is investigated using a flash X-ray facility. The experimental results show that the pulsed ionizing radiation causes voltage surges in the devices and the output voltage recovers linearly after transient disturbance exhibited by a negative peak and a positive peak. The recovery time depends on the amplitude of the positi...

2013
Stephan M. Huber Lena Butz Benjamin Stegen Dominik Klumpp Norbert Braun Peter Ruth Franziska Eckert

The standard treatment of many tumor entities comprises fractionated radiation therapy which applies ionizing radiation to the tumor-bearing target volume. Ionizing radiation causes double-strand breaks in the DNA backbone that result in cell death if the number of DNA double-strand breaks exceeds the DNA repair capacity of the tumor cell. Ionizing radiation reportedly does not only act on the ...

Journal: :International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 1977

2006
RONGHE ZHANG JINGXIA LI FREDRIC J. BURNS CHUANSHU HUANG

Carcinogenic effects of ionizing radiation and benzo[a]pyrene-7,8-diol-9,10-epoxide (B[a]PDE), a major metabolite of benzo[a]pyrene (B[a]P), have been well demonstrated both in vitro and in vivo. Two-stage carcinogenesis results indicate that mouse skin is highly susceptible to both ionizing radiation and benzo[a]pyrene-7,8-diol-9,10epoxide (B[a]PDE), a major metabolite of benzo[a]pyrene (B[a]P...

2017
Hongyun Shi Ke Zhang Ming Wen Yu Yuan

Objective: To discover the role of MCPH1 in the DNA double-strand damage induced by ionizing radiation and the relationship with H2AX in esophageal cancer cell ECA109. Methods: ECA109 cancer cells will be accepted 8 Gy 1 h after irradiation for protein extraction and immunofluorescence observed MCPH1 and H2AX protein expression and nuclear foci changes. Establish a stable low expression of H2AX...

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