Nisoldipine, a 1-4-dihydropyridine drug is determined by the development of simple and sensitive Extractive Spectrophotometric method. In the present study an ion-pair complex of amino derivative of the Nisoldipine with Bromocresol Green Solution in acidic medium is formed with subsequent extraction of the ion-pair complex in Chloroform. Maximum absorption was seen at the wavelength of 418 nm t...

The construction and general performance characteristics of three piezoelectric quartz crystal sensors responsive to the pentoxyverine are described here. This kind of non-potentiometric sensing method is based on use of ion-pair complexes of the pentoxyverine cation with three counter anions, namely, tungstophosphate, tetraphenylborate and picrolonate. The complexes were embedded in a PVC matr...

The binding efficiency of a series of monotopic () and heteroditopic () calix[4]arene-based receptors has been evaluated in chloroform solution toward N-methylpyridinium ion pairs using NMR and UV/vis spectroscopic techniques. These experiments provided evidence that, due to a positive cooperative effect, the presence of a phenylurea H-bond donor group on the upper rim of the calix[4]arene macr...

a conductance study of the interaction between cs+, rb+, nh4+, k+, t1+ and ag+ ions and18-crown-6 (18c6), benzo-18-crown-6 (b18c6), dicyclohexyl-18-crown-6 (dc18c6),dicyclohexyl-24-crown-8 (dc24c8), dibenzo-24-crown-8 (db24c8) in different binarymixtures of acetonitrile (an) with dimethylsulfoxide (dmso) and dimethylformamide (dmf)at 25 °c has been carried out. formation constants of the result...

The acidity constants of some amino acids (Am) were determined by potentiometric pH titration. The stability constants of the 1:1 complexes formed between M2+: Ca2+, Mg2+, Mn2+, Co2+, Ni2+, Cu2+ or Zn2+ and Am2-, were determined by potentiometric pH titration in aqueous solution (I = 0.1 M, NaNO3, 25°C). The order of the stability constants was reported. It is shown that the stability of the bi...

Target validation and selection are critical early steps in the drug discovery process as they trigger substantial activity and investment to identify potential drug candidates. Antibodies play a crucial role in target selection as they provide powerful tools to explore the distribution and subcellular location of candidate molecules and can also be used to explore function. For studies of ion ...

Cytochrome c oxidase (ferrocytochrome c: oxygen oxidoreductase, EC 1.9.3.1) has been resolved into a pair of complexes of unequal molecular weight. The larger complex (electron transfer complex) contains exclusively the oxidation-reduction proteins characteristic of cytochrome oxidase; the smaller complex (ion transfer complex) shows exclusively the capability for cation-dependent induction of ...

A pair of enantiopure mononuclear dysprosium/salen-type complexes (Et3NH)[Dy((R,R)/(S,S)-3-NO2salcy)2] (/), where 3-NO2salcyH2 represents N,N'-(1,2-cyclohexanediylethylene)bis(3-nitrosalicylideneiminato), are reported. The enantiomer contains two crystallographically independent dysprosium(iii) ions, each chelated by two enantiopure 3-NO2salcy(2-) ligands forming a [DyN4O4] core. Detailed magne...

First, Schiff base iminopyridine ligand has been prepared by the condensation between primary amine, dimethylaniline and active carbonyl group of pyridine carboxaldehyde, then related complexes were synthesized in methanol solution. The ligand and metal complexes have been characterized by elemental analysis, UV, IR, 1 H NMR and 13CNMR spectroscopy. The spectroscopic data of metal complexes ind...

With thiocyanate, zinc(II), cobalt(II) and copper(II) ions form stable anion, [M(SCN)4] . This anion in turn with methylene blue (MB) forms ion-pair of the type MB2[M(SCN)4] and turns methylene blue to violet. The stoichiometry and stability constants of the ion-association complexes were determined using BenesiHildebrand method and the stoichiometry was confirmed by Job’s continuous variation ...